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Investigating the role of frailty in the expression of dementia
(2020-08-28)
Background: Frailty is related to neuropathological features of Alzheimer’s disease (AD) as well as cognitive decline and dementia.
Objectives: 1) determine whether frailty moderates the relationship between neuropathology ...
A GENDER-BASED MULTI-METHODS SECONDARY STUDY OF AGE STEREOTYPES
(2020-06-25)
With the aging population, it is vital to understand how the psychosocial environment influences the well-being of the population. Aging is more than just physical change; it is also a psychosocial construct. Age-based ...
THE ASSOCIATION BETWEEN SELF-RATED HEALTH AND KEY INDICATORS OF HEALTH IN AN OLDER POPULATION: ANALYSIS OF THE CANADIAN LONGITUDINAL STUDY ON AGING
(2021-09-14)
Self-sated health (SRH) is a global indicator of health which reflects a person’s integrated perception of their own health. To obtain an in depth understanding of SRH, this study examined the association between SRH and ...
THE RELATIONSHIP BETWEEN HEARING AND FUNCTIONAL MOBILITY AMONG OLDER ADULTS AT BASELINE IN THE CANADIAN LONGITUDINAL STUDY ON AGING
(2021-08-31)
Mobility problems, prevalent among older adults, are influenced by numerous factors that are interrelated. The primary purpose was to examine the relationship between hearing, measured by Pure-Tone Audiometry, and mobility, ...
The relationship between frailty and the development and progression of HIV-Associated Neurocognitive Disorder (HAND)
(2021-04-12)
Background: The objective of this study was to determine the relationship between frailty and the development and progression of HIV-Associated Neurocognitive Disorder (HAND).
Methods: This study used data from the ...
Developing computational models to understand aging
(2021-12-17)
Aging in biological organisms is a complex process, involving changes at all levels of functioning. No single pathway or mechanism is responsible for aging, leading to the current understanding that aging is due to a number ...
Clinicopathological Correlates in Tauopathy and Aging
(2022-08-16)
Cognitive decline can result from both neurodegenerative or normal aging processes. Definitive diagnosis of many neurodegenerative diseases, such as Alzheimer’s disease (AD) and progressive supranuclear palsy (PSP), requires ...
EXPLORING TRANSIENT NEURAL EVENTS IN HEALTHY POPULATIONS USING NON-INVASIVE NEUROIMAGING
(2022-08-22)
Non-invasive neurophysiological recordings, like those measured by magneto/electro- encephalography (M/EEG), provide insight into the behaviour of neural networks and how these networks change with factors such as task ...
Psychometric Properties and Age-Related Effects of the Combined Attention Systems Test
(2023-04-25)
Attention is a multifaceted cognitive process that is important for functioning in daily life. The study of attention commonly focuses on three networks: alerting, orienting, and executive control. Despite the rich literature ...
Development of Adhesion Force microscopy for the surface charge analysis of collagen fibrils in vivo and in vitro
(2023-06-12)
Collagen fibrils are a key component of the extracellular matrix. In this study, we use the adhesion force between a silicon probe and a collagen substrate to demonstrate the sensitivity of adhesion force towards charge ...