Browsing by Subject "Schizophrenia"
Now showing items 1-7 of 7
-
Adolescent environmental challenges affect adult function in male and female Long Evans rats
(2014-05-01)Stress in adolescence is a putative risk factor for developing mental illnesses such as schizophrenia and mood disorders. Symptoms for these illnesses first emerge in late adolescence and early adulthood, with both incidence ... -
The Association of Anterior Cingulate Cortex Glutamate and Clozapine Eligibility In an Early Psychosis Sample
(2023-07-27)Background: The ability to identify patients who may benefit from clozapine at the earliest opportunity is important for maximizing long term outcomes in schizophrenia. Patients that meet criteria for treatment resistance ... -
Cognition in individuals at familial and clinical risk for severe mental illness
(2019-09-10)Severe mental illness (SMI) includes schizophrenia, bipolar disorder and severe and chronic major depressive disorder. SMI typically onsets early in the lifespan and causes significant impairments in functioning. Cognitive ... -
An Investigation into Caffeine Intake, Cognition, and Symptomatology in Schizophrenia Patients
(2019-08-29)Patients with schizophrenia consume significantly more caffeine than the general population. Despite this, few studies report on caffeine use, and even fewer on the association between caffeine intake and how it might ... -
An Investigation of the Auditory Mismatch Negativity Elicited by Complex Stimuli in Early-Phase Psychosis
(2019-08-30)Introduction: Reduction of mismatch-negativity (MMN) has been well characterized in individuals with chronic schizophrenia. However, there is a lack of MMN research in early-phase psychosis (EPP). We investigated MMN ... -
MICROSTRUCTURAL CHANGES IN FRONTAL WHITE MATTER ASSOCIATED WITH CANNABIS USE IN EARLY PHASE PSYCHOSIS: A DIFFUSION TENSOR IMAGING (DTI) STUDY
(2016-01-19)Introduction: This project aimed to examine the impact of cannabis use on the brain white matter (WM) tissue abnormalities associated with psychosis, in individuals at the early phase of psychosis (< 5 years from diagnosis). ... -
SLEEP REGULATION IN THE STOP-NULL MOUSE MODEL OF SCHIZOPHRENIA
(2014-03-13)Sleep disturbances are common in patients with schizophrenia. Mice lacking the cytoskeletal-associated protein Stable Tubule Only Polypeptide (STOP) display cognitive, behavioural and neurobiological deficits that mimic ...