Browsing by Subject "Osteoarthritis"
Now showing items 1-8 of 8
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Arthrocen & OA Pain Raw Data
(2018-01-25) -
CHARACTERISING THE NEUROPHYSIOLOGY OF POST-TRAUMATIC OSTEOARTHRITIS IN RATS AND THE INVOLVEMENT OF PROTEASE ACTIVATED RECEPTOR-4
Osteoarthritis (OA) affects 1 in 10 Canadians and is more prevalent in women than men. Remarkably, 60% of OA patients cite inadequate pain relief with current treatments. This may in part be due to multiple OA phenotypes ... -
Data Science Strategies for Modelling Total Knee Arthroplasty Patient Variability
Knee osteoarthritis (OA) can present through self-reported patient symptoms and joint-level manifestations, impairing mobility and function. Symptom relief and functional restoration of end-stage OA is typically treated ... -
The effect of knee joint effusion on gait mechanics and muscle activation characteristics in moderate knee osteoarthritis
Knee osteoarthritis (OA) is one of the most prevalent joint diseases, and knee effusion, as a manifestation of synovitis, is associated with knee OA clinical outcomes and disease progression. Thesis objectives were i) to ... -
Factors affecting knee joint muscle activation patterns during gait in individuals with knee osteoarthritis
(2012-01-03)Knee osteoarthritis (OA) is a progressive disease and a leading cause of morbidity in older adults, resulting in severe mobility limitations. While the osteoligamentous and neuromuscular systems are altered in knee OA, ... -
KNEE MECHANICS OF HEALTHY AND OSTEOARTHRITIC JOINTS
Objective: Knee Osteoarthritis (OA) can be the result of both mechanical and biological events that interfere with normal joint function. The aims of this thesis were to (1) quantify the biomechanical factors that ... -
OBESITY AND ITS INFLUENCE ON KNEE JOINT CONTACT FORCES IN INDIVIDUALS WITH MODERATE KNEE OSTEOARTHRITIS
(2014-08-22)Obesity is known as a major risk factor for the development and progression of knee OA. It has been proposed to affect the joint through linked mechanical and metabolic factors. However, its precise role in the pathomechanics ... -
Obesity is associated with higher absolute tibiofemoral contact and muscle forces during gait with and without knee osteoarthritis
(Elsevier, 2016-01)Background Obesity is an important risk factor for knee osteoarthritis initiation and progression. However, it is unclear how obesity may directly affect the mechanical loading environment of the knee joint, initiating ...
