Browsing by Subject "Mast cells"
Now showing items 1-3 of 3
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DELINEATING THE ROLE OF CALCINEURIN A ALPHA IN THE MAST CELL FCϵRI-MEDIATED IMMUNE RESPONSE
Allergies are a health challenge resulting from excessive and inappropriate responses to innocuous antigens (allergens), and a key cellular player is the mast cell. Mast cell activation by allergen initiates a response ... -
EXTRACELLULAR MITOCHONDRIA RELEASED FROM LIVER ISCHEMIA REPERFUSION INJURY ACT AS ALARMINS TO EVOKE INNATE IMMUNE SYSTEM AND TRIGGER INFLAMMATION
Ischemia reperfusion injury (IRI) during liver transplantation enhances the immunogenicity of allografts and thus impacts overall graft outcome. This sterile inflammatory insult is known to activate innate immunity and ... -
The role of mast cells and toll-like receptor 2 (TLR2) in host defence and pathology following Chlamydia infection
Chlamydia trachomatis (Ct) is the most common bacterial sexually transmitted infection and the leading cause of infectious blindness worldwide. A comprehensive understanding of immune responses to Ct, and how they lead to ...
