Browsing by Subject "KSHV"
Now showing items 1-5 of 5
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The complex kaposin locus of Kaposi's sarcoma-associated herpesvirus: defining a new role in the lytic viral replication cycle
(2019-04-02)Kaposi’s sarcoma-associated herpesvirus (KSHV) is the etiologic agent of the endothelial cell (EC) cancer, Kaposi’s sarcoma, and two B-cell malignancies. In infected cells, the virus exists in two states; the latent program ... -
KAPOSI’S SARCOMA-ASSOCIATED HERPESVIRUS PROTEIN, KAPOSIN B INDUCES THE SELECTIVE CATABOLISM OF PROCESSING BODIES
(2019-08-26)Kaposi’s sarcoma-associated herpesvirus (KSHV) is the causative agent of the inflammatory endothelial cell (EC) cancer, Kaposi’s Sarcoma (KS). Many inflammatory mRNAs (ARE-mRNAs) are subject to constitutive decay in ... -
KSHV vGPCR: A VIRAL ONCOPROTEIN THAT TRIGGERS AUTOPHAGY AND CELLULAR SENESCENCE
(2013-09-09)Autophagy (literally to ‘self-eat’) is an intracellular, catabolic mechanism to degrade and recycle cytoplasmic contents in response to metabolic, oxidative, and genotoxic stresses. Autophagy plays an important role in ... -
The Role of SUMOylation in the KSHV Kaposin B-MK2 Signaling Axis
(2019-12-16)Kaposi’s sarcoma (KS) is characterized by infection with Kaposi’s sarcoma associated herpesvirus (KSHV), aberrant inflammation and cell spindling. These phenotypes are recapitulated by expression of the viral gene product ... -
TRANSLATIONAL EFFICIENCY OF HERPESVIRUS MESSENGER RIBONUCLEIC ACIDS
(2020-06-08)Kaposi’s sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi’s sarcoma and primary effusion lymphoma. Herpesvirus genomes are decoded by host RNA polymerase enzymes, generating messenger ribonucleotides ...
