Browsing by Subject "KSHV"
Now showing items 1-5 of 5
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The complex kaposin locus of Kaposi's sarcoma-associated herpesvirus: defining a new role in the lytic viral replication cycle
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the etiologic agent of the endothelial cell (EC) cancer, Kaposi’s sarcoma, and two B-cell malignancies. In infected cells, the virus exists in two states; the latent program ... -
KAPOSI’S SARCOMA-ASSOCIATED HERPESVIRUS PROTEIN, KAPOSIN B INDUCES THE SELECTIVE CATABOLISM OF PROCESSING BODIES
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the causative agent of the inflammatory endothelial cell (EC) cancer, Kaposi’s Sarcoma (KS). Many inflammatory mRNAs (ARE-mRNAs) are subject to constitutive decay in ... -
KSHV vGPCR: A VIRAL ONCOPROTEIN THAT TRIGGERS AUTOPHAGY AND CELLULAR SENESCENCE
(2013-09-09)Autophagy (literally to ‘self-eat’) is an intracellular, catabolic mechanism to degrade and recycle cytoplasmic contents in response to metabolic, oxidative, and genotoxic stresses. Autophagy plays an important role in ... -
The Role of SUMOylation in the KSHV Kaposin B-MK2 Signaling Axis
Kaposi’s sarcoma (KS) is characterized by infection with Kaposi’s sarcoma associated herpesvirus (KSHV), aberrant inflammation and cell spindling. These phenotypes are recapitulated by expression of the viral gene product ... -
TRANSLATIONAL EFFICIENCY OF HERPESVIRUS MESSENGER RIBONUCLEIC ACIDS
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi’s sarcoma and primary effusion lymphoma. Herpesvirus genomes are decoded by host RNA polymerase enzymes, generating messenger ribonucleotides ...
