Browsing by Subject "Biomarkers"
Now showing items 1-3 of 3
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Characterizing metformin response and sensitivity biomarkers in breast cancer
The anti-diabetic drug metformin has been shown to exhibit broad in vitro and in vivo anti-neoplastic activity in various cancer types, including breast cancer. Despite numerous clinical trials ongoing, no targeted biomarkers ... -
Investigating the Association between Arsenic Exposure and Chronic Disease Using Toenail Speciation Biomarkers: A Pilot Study in Atlantic Canada
With the support of Atlantic PATH, this study has used the world’s largest collection of toenail samples to investigate the association between chronic disease and arsenic speciation. The results of our study showed no ... -
Towards the Development of a Proteomics Workflow for High-throughput Protein Biomarker Discovery
(2010-06-22)Two popular workflows exist for quantitative proteome analysis: two-dimensional polyacrylamide gel electrophoresis (2D-PAGE), with staining to visualize proteins, and multidimensional solution phase separations of isotopically ...