Browsing by Subject "Apoptosis"
Now showing items 1-5 of 5
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THE ANTICANCER ACTIVITY AND MECHANISMS OF ACTION OF JADOMYCINS IN MULTIDRUG RESISTANT HUMAN BREAST CANCER CELLS
(2018-09-28)Breast cancer is the most common cancer in women, and approximately one third of all breast cancers will ultimately metastasize. Metastatic breast cancer is classified as an incurable disease. The development of multidrug ... -
Oncolytic Reovirus Induces Intracellular Redistribution of Ras to Promote Apoptosis and Progeny Virus Release
(2014-08-22)Ras is a dynamic protein capable of interacting with plasma membrane microdomains and intracellular membranes. Its activity, as controlled by post-translational modifications, is essential in regulating cell growth, ... -
TRANSCRIPTION FACTOR EB REGULATES APOPTOSIS, DNA REPAIR, AND CELL PROLIFERATION IN TRIPLE-NEGATIVE BREAST CANCER CELLS
(2022-05-03)Breast cancer is the leading cause of cancer-related death among women in Canada. Molecular heterogeneity among breast cancer patients dictates survival outcomes and treatment selection, with triple-negative breast cancer ... -
Zebrafish Tools To Combat Acute Myeloid Leukaemia – The Nucleoporin 98 kiloDalton—Homeobox A9 (NUP98-HOXA9) Fusion Oncogene Drives Myeloproliferation By Upregulating DNA (Cytosine-5-)-Methyltransferase 1 (dnmt1)
(2018-02-12)We need to better understand the genetic mechanisms that transform normal blood cells into acute myeloid leukaemia (AML). Overall survival is improving for children and adults with AML, but traditional therapies can be ... -
Zinc-Silicate Glasses for Transarterial Chemoembolization of Hepatocellular Carcinoma
(2015)Drug eluting bead transarterial chemoembolization (DEB-TACE) has emerged as the gold standard therapy for patients diagnosed with hepatocellular carcinoma, the second leading cause of cancer-related deaths worldwide. ...