Browsing by Subject "transgenic"
Now showing items 1-3 of 3
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Aberrant Behaviour and Neural Activity in the 5xFAD Mouse Model of Alzheimer's Disease: Exploring Behavioural and Psychological Symptoms of Dementia in a Mouse Model of Amyloid Pathology
(2023-08-30)The present work examines behavioural and psychological symptoms of dementia (BPSD)-like behaviours in the 5xFAD mouse model of Alzheimer’s disease (AD)-related amyloid pathology. In particular, this work reviews BPSD-like ... -
The Analysis of Brn3a and Thy1-CFP as Potential Markers of Retinal Ganglion Cells after Optic Nerve Injury in Mice
(2013-07-05)Purpose: Retinal ganglion cell (RGC) loss is a measure of the progression of many visual disorders. It is important to identify RGCs with good specificity, so RGC numbers can be reliably analyzed. The purpose of this study ... -
CHARACTERIZATION OF SOCIAL DEFICITS IN THE 5XFAD MOUSE MODEL OF ALZHEIMER'S DISEASE
(2019-11-28)The 5xFAD mouse strain is a double-transgenic Alzheimer’s disease (AD) model containing mutant APP (K670N/M671L, I716V, and V717I) and PS1 (M146L and L286V) genes. Mice expressing these mutations have rapid accumulation ...