Browsing by Subject "lysosome"
Now showing items 1-2 of 2
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Inhibition of TRPML1 by Lysosomal Adenosine Accumulation Involved in ADA Diseases
(2017-05-11)Adenosine plays important roles in cells, and impaired adenosine homeostasis has been associated with numerous human diseases. Lysosomes are referred as the cellular recycling centers which generate adenosine by breaking ... -
ROLE OF TRANSCRIPTION FACTOR EB (TFEB) IN CARDIAC HEALTH AND DISEASE
(2020-12-18)Cardiomyopathy is prevalent and the leading cause of mortality among obese and diabetic patients. Abnormalities in cardiac energy metabolism trigger myocyte dysfunction that precedes the onset of cardiomyopathy. Lack of ...