Browsing by Subject "cross-coupling"
Now showing items 1-5 of 5
-
Advances in Nickel-Catalyzed C-N Cross-Coupling Enabled by Tailored Ancillary Ligand Design
(2018-12-05)The nickel-catalyzed Csp2-N cross-coupling of NH substrates and (hetero)aryl (pseudo)halides for the synthesis of (hetero)anilines is in the midst of a resurgence. Reactivity breakthroughs that have been achieved in this ... -
Advances in Nickel-Catalyzed C–O Cross-Coupling Reactions Enabled by Ancillary Ligand Design
(2023-12-04)The ubiquity of C(sp2)–N and C(sp2)–O linkages in active pharmaceutical ingredients, agrochemicals, and other biologically active compounds generates motivation for developing effective avenues for the formation of such ... -
The Development of Catalysts for the Monoarylation of Ammonia and Related Challenging Cross-Coupling Reactions
(2013-11-26)The use of homogeneous organometallic catalysis for otherwise challenging chemical transformations is a concept that has gained significant interest in recent decades, providing access to a variety of useful chemical ... -
Investigating the Design of Bisphosphine Ligands for use in Nickel-catalyzed C(sp2)-N Cross-Coupling
(2019-12-13)Notwithstanding the matured protocol of palladium-catalyzed C(sp2)-N cross-coupling (Buchwald Hartwig Amination, BHA), the development of nickel-based catalysts that carry out analogous transformations is motivated both ... -
A Systematic Investigation into Bisphosphine Ligands for Nickel-Catalyzed C(sp2)–N Cross-Coupling
(2023-04-10)Research into transition metal-catalyzed C–N cross-coupling reactions has been driven by a need for robust and facile synthetic routes towards bioactive molecules which are rich in C–N linkages. The use of Pd-based catalysts ...