Browsing by Subject "cholesterol"
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Characterization of the roles of neuronal cholesterol biosynthesis and ORP4 in hippocampal neurons and glia
(2018-01-05)Cholesterol is an essential component of cell membranes and plays important roles in cell signalling. The brain contains a quarter of the body’s total cholesterol pool, all of which is synthesized in situ by neurons and ... -
The effect of phosphorylation on oxysterol-binding protein (OSBP) sterol binding activity
(2012-09-11)Oxysterol binding protein (OSBP) binds 25-hydroxycholesterol (25OH) and cholesterol, which regulates PH and FFAT domain interaction with the Golgi apparatus and endoplasmic reticulum, respectively. Adjacent to these ...