Browsing by Subject "Metastasis"
Now showing items 1-6 of 6
-
Competing Influences Of The Tumor Microenvironment On CD26 And The Cancer Phenotype Of Colorectal Carcinoma Cells
(2013-05-01)In Canada, colorectal cancer is the second leading cause of cancer death for both men and women. There are many different factors that contribute to the progression and spread of the disease. However, increasing evidence ... -
Fish Tales: Loss of STAG2 Promotes Migration of Ewing Sarcoma
(2019-11-28)Ewing sarcoma (EwS) is a bone and soft tissue cancer affecting children and adolescents. The most unfavorable prognostic factor of EwS is the presence of metastasis, however this process is still poorly understood. Therefore, ... -
IN VITRO AND PRE-CLINICAL EVALUATION OF ANTI-METASTATIC ACTIVITY OF PHLORIDZIN DOCOSAHEXAENOATE (PZ-DHA) VERSUS TRIPLE-NEGATIVE BREAST CANCER
(2020-09-11)The World Health Organization identifies breast cancer as the most common cancer among women worldwide. Triple-negative breast cancer (TNBC) lacks receptors for estrogen (ER), progesterone (PR), and human epidermal growth ... -
Pepper-derived phytochemicals modulate metastatic processes in triple-negative breast cancer cells: a nanoparticle-based delivery approach
(2019-11-28)Metastasis and disease relapse are the primary determinant of cancer prognosis. The process of epithelial to mesenchymal transition (EMT) plays a crucial role in the induction of metastasis. Novel therapeutics are urgently ... -
THE ROLE OF THE IL-17/IL-17R AXIS IN BREAST TUMOR GROWTH AND METASTASIS
(2016-11-01)Clinical trials and animal experiments have revealed that chronic inflammation may contribute to all steps of tumor development from initiation, all the way to metastatic progression, predisposing for the development of ... -
Using Zebrafish Xenotransplantation To Study Ewing's Sarcoma And Investigate The Role Of Y-Box Binding Protein 1 In Metastasis
(2015-05-05)The most unfavourable prognostic factor for Ewing’s sarcoma (ES) is the presence of metastases. To date, a viable cancer model for ES metastasis has not been developed. Models for ES are crucial to uncovering the key ...