Browsing by Subject "Immunotherapy"
Now showing items 1-4 of 4
-
Exploring the contributions of 2B4 and CD48 to natural killer cell activation and cancer killing
(2024-07-21)Natural killer (NK) cells are known mediators of immunosurveillance and anti-cancer activity. They prevent cancer growth and relapse and are increasingly used for cancer immunotherapy. NK cells distinguish non-cancerous ... -
The Flavonoid Apigenin Inhibits Inducible Programmed Death Ligand 1 Expression by Breast Cancer Cells
(2018-02-12)Programmed death ligand 1 (PD-L1) is a T cell inhibitory molecule expressed by activated T cells and antigen presenting cells, as well as by various tumor types. PD-L1 expression is believed to contribute to immune evasion ... -
Local IL-15-immunotherapy to treat melanoma
(2017-12-15)Intratumoural (i.t.) IL-2 is an effective treatment for cutaneous, metastatic melanoma. However, treating patients with high metastatic burden can be very challenging. Another common γ chain cytokine, IL-15, facilitates ... -
Natural killer cells as immunotherapy to target rapidly evolving non-small cell lung carcinoma
(2021-07-06)Non-small cell lung carcinoma (NSCLC) is a hard-to-treat, high mortality cancer in need of more effective therapy options. Natural killer (NK) cells are innate lymphocytes that contribute to anti-tumor functions through ...