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dc.contributor.authorLam, Wan L.en_US
dc.date.accessioned2014-10-21T12:34:45Z
dc.date.available1991
dc.date.issued1991en_US
dc.identifier.otherAAINN64544en_US
dc.identifier.urihttp://hdl.handle.net/10222/55216
dc.descriptionGenetic tools have been developed for studying the molecular biology of the halophilic archaebacterium, Haloferax volcanii. Shuttle vectors and a transformation system facilitate direct cloning of archaebacterial genes, and allow the reintroduction of in vitro-altered DNA into Hf. volcanii. The archaebacterial genes isolated have in turn provided the necessary genetic markers for further development of strategies for genetic mapping and for direct manipulation of the chromosome.en_US
dc.descriptionSeveral of these genetic techniques are applied to describe genes for tryptophan biosynthesis and mevalonic acid biosynthesis, to determine the organization of functionally-related genes, and to map auxotrophic mutations to the Hf. volcanii chromosome.en_US
dc.descriptionThesis (Ph.D.)--Dalhousie University (Canada), 1991.en_US
dc.languageengen_US
dc.publisherDalhousie Universityen_US
dc.publisheren_US
dc.subjectBiology, Molecular.en_US
dc.titleGenetic analysis in Haloferax volcanii.en_US
dc.typetexten_US
dc.contributor.degreePh.D.en_US
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