Browsing Singer, Richard by Title

Now showing items 1-2 of 2

  • FACT, the Bur kinase pathway, and the histone co-repressor HirC have overlapping nucleosome-related roles in yeast transcription elongation 

    Stevens, J. R., A. F. O'Donnell, T. E. Perry, J. J. R. Benjamin, et al. 2011. "FACT, the Bur kinase pathway, and the histone co-repressor HirC have overlapping nucleosome-related roles in yeast transcription elongation." PLoS ONE 6(10).
    Gene transcription is constrained by the nucleosomal nature of chromosomal DNA. This nucleosomal barrier is modulated by FACT, a conserved histone-binding heterodimer. FACT mediates transcription-linked nucleosome disassembly ...

  • Mutational analysis of the Prt1 protein subunit of yeast translation initiation factor 3 

    Evans, D. R. H., C. Rasmussen, P. J. Hanic-Joyce, G. C. Johnston, et al. 1995. "Mutational analysis of the Prt1 protein subunit of yeast translation initiation factor 3." Molecular and cellular biology 15(8): 4525-4535.
    The Saccharomyces cerevisiae PRT1 gene product Prt1p is a component of translation initiation factor eIF-3, and mutations in PRT1 inhibit translation initiation. We have investigated structural and functional aspects of ...