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Synthesis and biological evaluation of prodigiosene conjugates of porphyrin, estrone and 4-hydroxytamoxifen

Hawco, Cassandra L.A.; Marchal, Estelle; Uddin, Md. Imam; Baker, Alexander E.G.; Corkery, Dale P.; Dellaire, Graham; Thompson, Alison (Bioorganic & Medicinal Chemistry, 2013)

To generate the first series of prodigiosene conjugates, the tripyrrolic skeleton was appended to estrone, tamoxifen and porphyrin frameworks by way of ester linkers and various hydrocarbon chain lengths. The ability of ...