Now showing items 1-10 of 40
Synthesis and Anticancer Activity of Prodigiosenes bearing C-Ring Esters and Amides
(Royal Society of Chemistry, 2017)
Asymmetric Dipyrrin and F-BODIPYs Conjugated to Terminal Alkynes and Alkenes
(American Chemical Society, 2017)
Asymmetric oxidation of 2-(arylsulfenyl)pyrroles
The asymmetric oxidation of prochiral 2-(arylsulfenyl)pyrroles has been investigated. A marked electronic effect within the substrate significantly influenced the degree of enantioselectivity obtained, with very high enantio ...
Synthesis of dipyrrins bearing chirality adjacent to the conjugated skeleton - Electron-poor pyrroles exhibit dramatically reduced nucleophilicity
With the aim of furthering our investigations into the asymmetric complexation of dipyrrinato ligands, a dipyrrin bearing a stereogenic centre directly adjacent to the conjugated skeleton was synthesized. The electron- ...
Synthesis of heteroleptic pyrrolide/bipyridyl complexes of ruthenium(II)
The synthesis and characterization of the first heteroleptic pyrrolide/2,2'-bipyridyl complexes of ruthenium(II) are reported. Pyrroles substituted at the 2-position with X = O functionality react with Ru(bipy)(2)Cl-2.2H(2)O ...
Microwave-accelerated synthesis of benzyl 3,5-dimethyl-pyrrole-2-carboxylate
Benzyl 3,5-dimethyl-pyrrole-2-carboxylate, a very useful pyrrole in porphyrin and dipyrromethene synthesis, can be synthesized via the Knorr-type reaction, but in low yield. Alternative routes to benzyl 3,5-dimethyl-pyrr ...
Chiral molecules containing the pyrrole framework
This review summarizes strategies by which chiral pyrroles, both simple and complex, have been prepared: strategies include formation of the pyrrolic ring using starting materials appended with chirality, as well as the ...
Investigations regarding the utility of prodigiosenes to treat leukemia
Prodigiosenes, possessing a 4-methoxypyrrolyldipyrrin skeleton, are known for their anti-cancer activity. Structural modification of the C-ring resulted in a series of prodigiosenes that displayed promising activity against ...