Browsing Pediatrics Faculty Research, Publications and Presentations by Title
Now showing items 14-33 of 34
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Global challenges of implementing human papillomavirus vaccines
Human Papillomavirus vaccines are widely hailed as a sweeping pharmaceutical innovation for the universal benefit of all women. The implementation of the vaccines, however, is far from universal or equitable. Socio- ... -
Just Evidence: Opening Health Knowledge to a Parliament of Evidence
In this chapter, we present a complementary perspective to the oceans theme of this volume by ethnographically engaging the circulation of scientific knowledge and evidence in a different but comparable policy decision-making ... -
Lueurs et leurres de la santé globale À propos de MenAfriVac®, un vaccin « africain » contre la méningite
In biomedical narratives, the Meningitis Vaccine Project (MVP) enabled the technology transfer for the development and implementation of MenAfriVac® vaccine at an affordable price for African countries. The presentation ... -
Maternal pre-pregnancy weight status and health care use for mental health conditions in the offspring
Objectives: The objective of this study was to examine the relationship between pre-pregnancy maternal weight status and offspring physician visits for mental health conditions in childhood and adolescence. Methods: We ... -
Oncogenic ras-induced downregulation of a pro-apoptotic protease caspase-2 is required for malignant transformation of intestinal epithelial cells
Resistance of carcinoma cells to anoikis, apoptosis that is normally induced by loss of cell-to-extracellular matrix (ECM) adhesion, is thought to be essential for the ability of these cells to form primary tumors, invade ... -
Prepared for the “unexpected”? Lessons from the 2014-16 Ebola epidemic in West Africa on integrating emergent theory designs into outbreak response.
Summary Box 1. Even seemingly straightforward interventions, such as vaccine delivery, require real-time awareness of emergent on-the-ground local (‘field’) realities. 2. Outbreak response requires thoughtful engagement ... -
Rendre évident: une approche symétrique de la réglementation des produits thérapeutiques
ENGLISH: Within the social studies of science, risk regulation regimes dominated by a technocratic approach are critiqued for neglecting public, socially situated epistemological standpoints, which, it is argued, are more ... -
Risks of nutrigenomics and nutrigenetics? What the scientists say.
Nutrigenomics and nutrigenetics (hereafter NGx) have stimulated expectations for beneficial applications in public health and individuals. Yet, the potential achievability of such promise is not without socioethical ... -
Substitute Decision Making About Research: Identifying the Legally Authorized Representative in Four Canadian Provinces
Canada's aging population presents new incentives for research on Alzheimer's and other forms of dementia. But the public interest in advancing knowledge about these diseases must be partnered with a concern for exploitation, ... -
Technologies of trust in epidemic response: openness, reflexivity and accountability during the 2014-2016 Ebola outbreak in West Africa
Trust is an essential component of successful cooperative endeavours. The global health response to the 2014–2016 West Africa Ebola outbreak confronted historically tenuous regional relationships of trust. Challenging ... -
Tumor suppressor protein kinase Chk2 is a mediator of anoikis of intestinal epithelial cells
Resistance of carcinoma cells to anoikis, apoptosis that is normally induced by detachment of non-malignant epithelial cells from the extracellular matrix, is thought to be critical for carcinoma progression. Molecular ...