Browsing Pediatrics Faculty Research, Publications and Presentations by Title
Now showing items 9-28 of 34
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Exploring the post-genomic world: differing explanatory and manipulatory functions of post-genomic sciences
Richard Lewontin proposed that the ability of a scientific field to create a narrative for public understanding garners it social relevance. This article applies Lewontin’s conceptual framework of the functions of science ... -
Faster access to new drugs: Fault lines between Health Canada’s regulatory intent and Industry innovation practices
Since 2003, Health Canada has been undergoing regulatory modernization to “ensure that Canadians have faster access to the safe drugs they need.” As national health agencies develop policies to modernize the regulation ... -
Frailty, fitness and late-life mortality in relation to chronological and biological age
Background: People age at remarkably different rates, but how to estimate trajectories of senescence is controversial. Methods: In a secondary analysis of a representative cohort of Canadians aged 65 and over (n = 2914) ... -
Global challenges of implementing human papillomavirus vaccines
Human Papillomavirus vaccines are widely hailed as a sweeping pharmaceutical innovation for the universal benefit of all women. The implementation of the vaccines, however, is far from universal or equitable. Socio- ... -
Just Evidence: Opening Health Knowledge to a Parliament of Evidence
In this chapter, we present a complementary perspective to the oceans theme of this volume by ethnographically engaging the circulation of scientific knowledge and evidence in a different but comparable policy decision-making ... -
Lueurs et leurres de la santé globale À propos de MenAfriVac®, un vaccin « africain » contre la méningite
In biomedical narratives, the Meningitis Vaccine Project (MVP) enabled the technology transfer for the development and implementation of MenAfriVac® vaccine at an affordable price for African countries. The presentation ... -
Maternal pre-pregnancy weight status and health care use for mental health conditions in the offspring
Objectives: The objective of this study was to examine the relationship between pre-pregnancy maternal weight status and offspring physician visits for mental health conditions in childhood and adolescence. Methods: We ... -
Oncogenic ras-induced downregulation of a pro-apoptotic protease caspase-2 is required for malignant transformation of intestinal epithelial cells
Resistance of carcinoma cells to anoikis, apoptosis that is normally induced by loss of cell-to-extracellular matrix (ECM) adhesion, is thought to be essential for the ability of these cells to form primary tumors, invade ... -
Prepared for the “unexpected”? Lessons from the 2014-16 Ebola epidemic in West Africa on integrating emergent theory designs into outbreak response.
Summary Box 1. Even seemingly straightforward interventions, such as vaccine delivery, require real-time awareness of emergent on-the-ground local (‘field’) realities. 2. Outbreak response requires thoughtful engagement ... -
Rendre évident: une approche symétrique de la réglementation des produits thérapeutiques
ENGLISH: Within the social studies of science, risk regulation regimes dominated by a technocratic approach are critiqued for neglecting public, socially situated epistemological standpoints, which, it is argued, are more ...