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Tumor suppressor protein kinase Chk2 is a mediator of anoikis of intestinal epithelial cells
(International Journal of Cancer, 2011-11-02)
Resistance of carcinoma cells to anoikis, apoptosis that is normally induced by detachment of non-malignant epithelial cells from the extracellular matrix, is thought to be critical for carcinoma progression. Molecular ...