Now showing items 1-2 of 2
The clinical meaningfulness of ADAS-Cog changes in Alzheimer’s disease patients treated with donepezil in an open-label trial
(BMC Springer Nature, 2007-08-30)
Background: In 6-month anti-dementia drug trials, a 4-point change in the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) is held to be clinically important. We examined how this change compared with ...
Frailty, fitness and late-life mortality in relation to chronological and biological age
(BMC Springer Nature, 2002-02-27)
Background: People age at remarkably different rates, but how to estimate trajectories of senescence is controversial. Methods: In a secondary analysis of a representative cohort of Canadians aged 65 and over (n = 2914) ...