Sodium methyl hex-5-ynoyl phosphate (SMHP) was synthesized as an activity-based probe designed to target protein architectures with nucleophiles adjacent to a cationic binding site. Activity-based protein profiling revealed ...

Despite many drawn parallels between carbon and phosphorus, the development of catena-phosphorus chemistry is superficially explored when compared to carbon. This lack of progression is especially highlighted for cationic ...

Thermochromic materials undergo temperature-dependent colour changes. Although there are several origins of thermochromism, two distinct types of thermochromism are common in thermochromic mixtures. Melt-lightened ...

This thesis investigates how memory is stored and transferred in rural landscapes by analyzing fading cultural histories evidenced in a set of lines in Mabou, Cape Breton, in Nova Scotia, Canada. Traces of the past manifest ...

A recent study discovered elevated levels of lysophosphatidic acid (LPA) in the synovial fluid of OA patients (Eli Lilly, unpublished). LPA is required for the initiation of neuropathic pain (Inoue, 2004), and therefore, ...

The mass emigration of rural peasants to the urban communities of America and Britain is a central episode in the history of nineteenth-century Ireland. The development of an Irish community in Halifax, Nova Scotia, is one ...

Sepsis is characterized by a dysregulated immune response to infection, causing damage to tissues and organs. As part of the inflammatory response, iron catalyzes the generation of reactive oxygen species (ROS). In the ...

Global, national and local institutions are adopting coastal management strategies that attempt to facilitate conservation without undermining socioeconomic development. Recently, two global conservation trends have developed ...