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EXPLORING THE RELATIONSHIP BETWEEN ECONOMIC INSECURITY AND HEALTH OUTCOMES
(2015-04-06)
This dissertation examines the relationship between economic insecurity and health outcomes for Canadians age 25 to 64 using the National Population Health Survey (NPHS) - a longitudinal dataset. Chapter 2 examines the ...
Tumor necrosis factor-{alpha} amplifies adipose-derived chemerin production and bioactivation
(2013-03-20)
Due to its escalating prevalence, obesity is becoming a leading cause of morbidity and mortality worldwide. Obesity is a complex health problem accompanied by metabolic abnormalities and low-grade inflammation that increases ...
Economic Determinants of Obesity in Canadian Adults
(2012-08-30)
This paper examines how socioeconomic status and economic insecurity relate to obesity in working-age Canadians between 2000 and 2010. First, I attempt to explain the gender specific gradients in body mass. Second, I test ...
DEVELOPMENT OF A CHEMOKINE-LIKE RECEPTOR 1 BIOASSAY TO STUDY THE IMPACT OF OBESITY ON ACTIVE CHEMERIN PRODUCTION IN OBESE HUMANS
(2014-12-17)
Prochemerin is an adipose-secreted molecule that is cleaved by extracellular proteases of the inflammatory, coagulation, and fibrinolytic cascades to active chemerin. Plasma and serum total chemerin (prochemerin + active ...
CHEMERIN REGULATES ADIPOSITY AND ENERGY HOMEOSTASIS
(2011-11-08)
Obesity, characterized by an excess of adipose tissue, is an established risk factor
for cardiovascular disease and type II diabetes. Different mechanisms linking obesity with
these comorbidities have been postulated but ...
OBESITY AND ITS INFLUENCE ON KNEE JOINT CONTACT FORCES IN INDIVIDUALS WITH MODERATE KNEE OSTEOARTHRITIS
(2014-08-22)
Obesity is known as a major risk factor for the development and progression of knee OA. It has been proposed to affect the joint through linked mechanical and metabolic factors. However, its precise role in the pathomechanics ...
Validation of a Commercial Three-Dimensional Whole-Body Laser Scanner for the Collection of Obesity-Related Measurements
(2014-09-03)
This study aimed to develop a systematic method of comparing manual and digital anthropometric measurements and validate a commercial three-dimensional laser scanner, for measurements related to obesity. Firstly, novel ...
AUTOTAXIN IS NUTRITIONALLY REGULATED AND ALTERS MITOCHONDRIAL FUNCTION IN OBESITY-INDUCED INSULIN RESISTANCE
(2019-08-28)
The skeletal muscle is a major site of insulin stimulated glucose disposal. Skeletal muscle insulin sensitivity can be influenced by multiple circulating nutritional, hormonal, neuronal and bioactive factors, including ...
THE ROLE OF LYSOPHOSPHATIDIC ACID AND AUTOTAXIN IN OBESITY-INDUCED CARDIAC INSULIN RESISTANCE
(2017-08-09)
The metabolic changes to adipose tissue during obesity can induce cardiac insulin resistance. During obesity and diabetes, cardiac metabolic flexibility is reduced, which may lead to impaired ATP production, elevated ...
ASSESSMENT OF RESPIRATORY SYSTEM MECHANICS IN ADULTS: EFFECT OF WEIGHT LOSS, POSTURE, BRONCHODILATION AND ARTEFACTS ON RESPIRATORY IMPEDANCE AND ITS REPEATABILITY
(2016-09-29)
Obesity is associated with respiratory symptoms that often improve with weight loss. However, traditional methods of testing pulmonary function such as spirometry and plethysmography show little or no changes with weight ...