Browsing by Subject "CFTR"
Now showing items 1-2 of 2
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Increased VIP Receptor Expression Mediates CFTR Membrane Localization in Response to VIP Treatment in VIP Knockout Mice
(2011-09-06)Cystic Fibrosis (CF) is caused by mutations in CFTR, a protein for chloride efflux in epithelial cells. VIP is a peptide that activates CFTR and improves membrane stability; VIP has 3 receptors VPAC1, VPAC2 and PAC1 that ... -
Phosphorylation-dependent Changes in the R-region Interactions Contribute to Regulation of the CFTR Chloride Channel
(2020-09-11)Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), the defective protein in cystic fibrosis, is an ion channel regulated by PKA and PKC phosphorylation of its regulatory region (R-region) through a mechanism still ...