| dc.contributor.author | Mann, Valerie Mary. | en_US |
| dc.date.accessioned | 2014-10-21T12:34:41Z | |
| dc.date.available | 1989 | |
| dc.date.issued | 1989 | en_US |
| dc.identifier.other | AAINN64458 | en_US |
| dc.identifier.uri | http://hdl.handle.net/10222/55187 | |
| dc.description | The enrollment of children in day care centres (DCC) is increasing rapidly. Infectious agents, such as cytomegalo-virus (CMV), transmitted by close personal contact may be spread among the congregated children. DCC children from middle socioeconomic families have been shown to have higher CMV prevalences when compared to children cared for at home. No data were available for CMV prevalence and transmission in Canadian day care centre populations. | en_US |
| dc.description | A survey of children attending Halifax, Nova Scotia day care centres was undertaken to determine the CMV excretion prevalence, to compare the CMV prevalence with reported day care centre population excretion prevalences and to the CMV seroprevalence in Halifax children surveyed approximately 20 years prior, and to determine whether CMV transmission had occurred. | en_US |
| dc.description | Urine excretion of CMV by children attending five Halifax day care centres was used to determine CMV prevalence. Transmission data were obtained by repeatedly surveying the children attending one day care centre. Demographic information was collected by survey form. | en_US |
| dc.description | Ten children from 75 children attending the five day care centres excreted CMV during a point survey. No risk factors could be identified for acquisition of CMV. The CMV excretion prevalence did not vary greatly from the seroprevalence found in the general Halifax children population 20 years prior. The CMV transmission data obtained from the repeated surveying of the population attending one day care centre yielded 13 of the 72 children participating excreting CMV, for a total of 20 CMV isolates. Two groupings of viral isolates were identified by restriction endonuclease analysis; one virus strain was excreted by two children during the first survey and the second strain was isolated from two children during separate surveys indicating the occurrence of CMV transmission among the day care center children. CMV transmission among children attending Halifax day care centres was found to be a rare event. | en_US |
| dc.description | Thesis (Ph.D.)--Dalhousie University (Canada), 1989. | en_US |
| dc.language | eng | en_US |
| dc.publisher | Dalhousie University | en_US |
| dc.publisher | | en_US |
| dc.subject | Health Sciences, Public Health. | en_US |
| dc.title | Cytomegalovirus shedding and transmission among children attending Halifax day care centres: A molecular epidemiological study. | en_US |
| dc.type | text | en_US |
| dc.contributor.degree | Ph.D. | en_US |
