Browsing by Subject "Sonic hedgehog"
Now showing items 1-2 of 2
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Investigating Tom1 as a Candidate Regulator of Ptch1
(2012-12-14)Sonic hedgehog (Shh) is a signaling molecule that is involved in patterning the embryo and regulates adult stem cell homeostasis. Patched1 (Ptch1) is the receptor for Shh and upon binding to Shh is endocytosed, allowing ... -
MACROPHAGE AEBP1 CONTRIBUTES TO MAMMARY EPITHELIAL CELL HYPERPLASIA AS A NOVEL REGULATOR OF SONIC HEDGEHOG SIGNALLING
(2012-12-14)Chronic inflammation stimulates mammary tumourigenesis by disrupting signalling interactions between the epithelial ducts and the surrounding stromal microenvironment. Adipocyte enhancer-binding protein 1 (AEBP1) promotes ...