dc.contributor.author | Riel, Hayley | |
dc.date.accessioned | 2019-08-30T10:55:01Z | |
dc.date.available | 2019-08-30T10:55:01Z | |
dc.date.issued | 2019-08-30T10:55:01Z | |
dc.identifier.uri | http://hdl.handle.net/10222/76359 | |
dc.description.abstract | Introduction: Reduction of mismatch-negativity (MMN) has been well characterized in individuals with chronic schizophrenia. However, there is a lack of MMN research in early-phase psychosis (EPP). We investigated MMN elicited by complex stimuli in EPP, hypothesizing that the complexity of MMN stimuli is better suited for identifying deficits in individuals with EPP. Methods: Thirteen EPP patients and 33 controls were included in the study. Demographic, symptom severity, and functional data were collected. MMN was measured with a novelty and emotional paradigm. Results: The groups did not differ in MMN amplitude. We observed a shorter latency for the EPP group and correlations between MMN, negative symptoms, and overall functioning within the novelty paradigm. Discussion: Our hypothesis was not supported as we observed no between-group differences. Our results support that good social and occupational functioning is associated with better sensory processing and that shorter MMN latencies is associated with positive psychotic symptoms. | en_US |
dc.language.iso | en | en_US |
dc.subject | Schizophrenia | en_US |
dc.subject | Psychosis | en_US |
dc.subject | Event-related potentials | en_US |
dc.title | An Investigation of the Auditory Mismatch Negativity Elicited by Complex Stimuli in Early-Phase Psychosis | en_US |
dc.date.defence | 2019-07-29 | |
dc.contributor.department | Department of Psychiatry Research | en_US |
dc.contributor.degree | Master of Science | en_US |
dc.contributor.external-examiner | Dr. Alissa Pencer | en_US |
dc.contributor.graduate-coordinator | Dr. Sherry Stewart | en_US |
dc.contributor.thesis-reader | Dr. Kim Good | en_US |
dc.contributor.thesis-reader | Dr. Jacob Cookey | en_US |
dc.contributor.thesis-supervisor | Dr. Philip Tibbo | en_US |
dc.contributor.thesis-supervisor | Dr. Derek Fisher | en_US |
dc.contributor.ethics-approval | Received | en_US |
dc.contributor.manuscripts | Not Applicable | en_US |
dc.contributor.copyright-release | No | en_US |