Meinertzhagen, Ian A.
I.A. Meinertzhagen, Ph.D., D.Sc.
University Research Professor
Drosophila ABC transporter mutants white, brown and scarlet have altered contents and distribution of biogenic amines in the brain Monoamines such as dopamine, histamine and serotonin (5-HT) are widely distributed throughout the brain of the fruit fly Drosophila melanogaster, where many of their actions have been investigated. For example, histamine ...
The metabolism of histamine in the Drosophila optic lobe involves an ommatidial pathway: beta-alanine recycles through the retina Flies recycle the photoreceptor neurotransmitter histamine by conjugating it to beta-alanine to form beta-alanyl-histamine (carcinine). The conjugation is regulated by Ebony, while Tan hydrolyses carcinine, releasing ...