***NOTE: Profile in development***

Pollen K.F. Yeung, BSc.Pharm., M.Sc., Ph.D.

Pharmacokinetics & Metabolism Laboratory
College of Pharmacy & Department of Medicine
Faculties of Health Professions & Medicine, Dalhousie University
Burbidge Building, Halifax, Nova Scotia, Canada B3H 4R2
Office: (902)494-3845; Lab: 494-3869; Fax: 494-1396
Email: Pollen.Yeung@Dal.Ca
http://myweb.dal.ca/pkyeung

Bio

Dr. Yeung is currently Professor of Pharmacy and Medicine in Dalhousie University (Halifax, NS, Canada). His research interest is in the area of pharmacokinetics, metabolism and biomarker assessment or cardiovascular and anti-cancer drugs. He is an active contributor and consultant for many academic and professional organizations, pharmaceutical industry, granting councils and the Government. He is currently a member on the Board of the Canadian Society of Pharmaceutical Sciences (CSPS), a member on the Editorial Board for Recent Review of Clinical Trials, Drug Metabolism Open Journal, Metabolites and Medical Sciences Monitor. He was the Vice Chair of the Cardiovascular, Pulmonary and Renal (CPR) Section of American Society of Clinical Pharmacology and Therapeutics (ASCPT) from 2006 -2010, a member of the Board of Biotechnology Life Sciences Industry Association in Nova Scotia (BioNova) from 1999 – 2007, Scientific Officer for Nova Scotia Health Research Foundation from 2009 -2011, Member of the Scientific Advisory Committee on Oncology Therapies for Health Canada from 2004 – 2007.

Publications:

Yeung, PKF and Seeto, D. A pilot study of the effect of isoproterenol on red blood cell concentrations of adenine nucleotides in a freely moving rat model in vivo (2012 submitted).

Feridooni, T, MacDonald, C, Shao, Di, Yeung, PKF, Agu, RU Cardio-protective potential of antiischemic drugs against chemotherapy-induced cardiotoxicity in H9C2 cell line. (2012 submitted).

Li, H, Li,PY and Yeung, PKF. A simple and specific HPLC assay of ginsenoside-Rh2 in plasma and its application for pharmacokinetic study in rats. (2012 submitted).

Yeung, PKF, Dauphinee, J and Marcoux, T. Effect of exercise on cardiovascular hemodynamic and red blood cell concentrations of purine nucleotides in normotensive vs hypertensive rat models in vivo.

Yeung, PKF and Narayanan, S. Hemodynamic effects of cladribine in a restrained rat model. Current Topics in Pharmacology 15 (1): 39 – 42, 2011. http://www.researchtrends.net/tia/title_issue.asp?id=11&in=1&vn=15&type=3

Yeung, PKF, Alcos, A, Marcoux, T and Tang, J. Comparing Pharmacokinetics and Metabolism of Diltiazem in Normotensive Sprague Dawley and Wistar Kyoto Rats vs Spontaneously Hypertensive Rats in vivo. Drug Metabolism and Drug Interactions 26 (3): 119 – 125, 2011.

Yeung,PKF, Alcos, A, Tang J. Comparing pharmacokinetics and hemodynamic effects of diltiazem between normotensive SD rats, normotensive WKY rats, and hypertensive SHR rats (2011 in preparation).

Yeung,PKF, Alcos, A, Tang J. Pharmacokinetics and hemodynamic effects of anti-ischemia drugs (2011 in preparation).

Yeung, PKF, Dauphinee, J, Gouzoules, T, and Simonson, K. and Schindler, C. Exercise improves hemodynamic profiles and increases RBC concentrations of purine nucleotides in a rodent model. Therapeutic Advances in Cardiovascular Diseases 4 (6): 341 – 347, 2010.

Yeung, PKF, Dauphinee, J, Simonson, K, and Gouzoules, T. Anti-Ischemia Drugs have no Effect on the In Vivo Metabolism of ATP by RBC in Normotensive Restrained Rats. The Open Drug Metabolism Journal 5: 1-6, 2011. http://www.benthamscience.com/open/todmj/articles/V005/1TODMJ.pdf

Amoaka-Fuffour, M , Yeung, PKF, Agu, RM. Permeation of losartan across human respiratory epithelium: An in vitro study with CALU-3 cells, Acta Pharmaceutica 59: 395 – 405, 2009.

Yeung,PKF, Tang, JL, Alcos,A. Hemodynamic effects of diltiazem, losartan, amlodipine and dipyridamole in a rat model following multiple doses in vivo . Current Topics in Pharmacology 13 (1): 41 – 46, 2009.

Rygier, LC, Yeung, PKF, and Berman, JN. Cladribine inhibits a diltiazem-induced increase in RBC purine nucleotide concentrations in a zebrafish model, Biomarkers 14:554 – 559, 2009.

Yeung, PkF, Alcos, A, Tang J. Pharmacokinetics and hemodynamic effects of diltiazem in rats following single vs multiple doses in vivo. The Open Drug Metabolism Journal (Open Access) 3 (7):

55 - 62: 2009 (http://www.bentham.org/open/todmj/openaccess2.htm)

Yeung, PKF, King, B, Narayanan, S, and Li, LM. Pharamcokinetics of cladribine in a rat model following subcutaneous and intra-arterial injections, Drug Metabolism and Drug Interactions 23: 291 – 298, 2008.

Yeung, PKF, Alcos, A, Tang, J, and Casley,WL. Hemodynamic effects of diltiazem in spontaneously hypertensive rats vs normotensive rats following multiple doses in vivo. Current Topics in Pharmacology 12 (1): 39-44, 2008. http://www.researchtrends.net/tia/article_pdf.asp?in=1&vn=12&tid=11&aid=2561

Yeung, PKF, Ding, L, Casley, WL. HPLC assay with UV detection for determination of RBC purine nucleotides concentrations and application for biomarker study in vivo. Journal of Pharmaceutical and Biomedical Analysis 47 (2): 377 – 382, 2008.

Yeung, PKF, Alcos,A, Tang,J, and Casley,WL. Pharmacokinetics and Metabolism of Diltiazem Following Multiple Doses: Comparing Normotensive Rat vs Hypertensive Rat Models in vivo. Drug Metabolism Letter 2 (2): 146 – 150, 2008.

Yeung, PKF, Ferguson. C. Jarrar, A., King, B., Li, ML. Development and validation of a sensitive and specific HPLC assay of cladribine for pharmacokinetics studies in rats. Journal of Pharmacy and Pharmaceutical Sciences 10 (2): 229-234, 2007.

Yeung,PKF, Alcos,A, Tang,J, Tsui,B. Pharmacokinetics and Metabolism of Diltiazem in Rats: Comparing Single vs Repeated Subcutaneous Injections in vivo. Biopharmaceutics and Drug Disposition 28:403-407.2007.

Yeung, PKF; Feng, JD, and Fice, D. Exercise hemodynamic and neurohormone responses as sensitive biomarkers for diltiazem in rats. J Pharm Pharmaceut Sci. 2006; 9(2):245-251.

Yeung,PKF, Feng,JDZ and Fice,D. Pharmacodynamic interactions between diltiazem and adenosine. Current Topics in Pharmacology, Current Topics in Pharmacology, Vol. 9(1), 117 – 121, 2005.

Yeung,PKF, Feng,J.D.Z., and Buckley,S.J. Effect of administration route and length of exposure on pharmacokinetics and metabolism of diltiazem in dogs. Drug Metabolism and Drug Interactions 18: 251 - 262, 2001

Yeung,PKF, Jamieson, A, Smith,GJ, Fice,D and Pollak,PT. Determination of plasma concentrations of losartan in patients by HPLC using solid phase extraction and UV detection, International Journal of Pharmaceutics 204: 17-22, 2000.

Yeung,P.K.F., Hung, O.R., Pollak, P.T., and Klassen, G.A. Pharmacokinetics and haemodynamic effects of diltiazem in healthy volunteers: Comparing resting with the effect of exercise. International Journal of Clinical Pharmacology and Therapeutics 37: 413-416, 1999.

Wang,Y., Fice,D.S., and Yeung, P.K.F. A simple high performance liquid chromatography assay for simultaneous determination of plasma norepinephrine, epinephrine, dopamine and 3,4- dihydroxyphenyl acetic acid. J. Pharm. Biomed. Anal. 21:519 - 525, 1999.

Feng, J.D.Z., and Yeung,P.K.F. High performance liquid chromatography assay for adenosine, guanosine and the oxypurine metabolites in plasma. Therapeutic Drug Monitoring, 22: 177 - 183, 2000.

Yeung,PKF, Feng,J.D.Z., and Buckley,S.J. Pharmacokinetics and hypotensive effect of diltiazem in rabbits: Comparing diltiazem to its major metabolites, J. Pharm. Pharmacol. 50: 1247-1253, 1998.

Yeung,PKF, Feng,J.D.Z., and Buckley,S.J. Pharmacokinetics and hypotensive effect of diltiazem in rabbits after a single intravenous administration: Effect of phenobarbital. Drug Metabolism and Drug Interaction, 14: 179 - 192, 1998.

Tsui,B.C.H., Feng, J.D.Z., and Yeung, P.K.F. Pharmacokinetics and haemodynamic effect of diltiazem in rats: Effect of route of administration. J. Pharm. Pharmacol. 50: 183-188, 1998.

Yeung,P.K.F., Feng,J.D.Z., and Buckley,S.J. Pharmacokinetics and hypotensive effect of deacetyl N-monodesmethyl diltiazem (M2) in rabbits after a single intravenous administration. Eur. J. Drug Metab. Pharmacok. 23: 27 - 31, 1998.

Yeung,P.K.F., Little,R., Jiang,Y.Q., Buckley,S.J., and Pollak,P.T. A simple high performance liquid chromatography assay for simultaneous determination of omeprazole and metronidazole in human plasma and gastric fluid. J. Pharm. Biomed. Analysis 17: 1393 - 1398, 1998.

Yeung,P.K.F., Feng,J.D.Z., and Buckley, S.J. Pharmacokinetics and haemodynamic effect of deacetyl diltiazem (M1) in rabbits after a single intravenous administration. Biopharm. Drug Disp. 19:109-113, 1998.

Yeung,P.K.F., Buckley,S.J., Hung, O.R., Pollak,P.T., Barclay,K.D., Feng,J.D., and Klassen,G.A.: Effect of diltiazem on plasma concentrations of oxypurines and uric acid. Therap. Drug Monit. 19:286-291, 1997.

Klassen,G.A., Yeung,P.K.F., Barclay,K.D., Pollak,P.T., Hung,O.R., Buckley,S.J.: The effects of diltiazem on intra-arterial blood pressure and heart rate during stress testing in patients with angina: A gender comparison study. J. Clin. Pharmacol. 37:297-303, 1997.

Yeung,P.K.F., Buckley,S.J., Pedder, S.C.J., and Dingemanse,J.: Determination of 3,4- dihydroxyphenylacetic acid (DOPAC) and 5-hydroxyindoleacetic acid (5-HIAA) in human plasma by a simple and rapid high performance liquid chromatography assay. J. Pharm. Sci. 85:451-454, 1996.

Veldhuyzen Van Zanten, SJO, Pollak, P.T., Kapoor, H., and Yeung, P.K.F.: The effect of omeprazole on the secretion of intravenously administered metronidazole into gastric juice: Implications for the treatment of Helicobacter pylori infection. Digestive Diseases and Sciences 41:1845-1852, 1996.

Yeung,PKF, Buckley,SJ, Hung,OR, Pollak,PT, Barclay,KD, Feng,JDZ, Farmer,PS and Klassen,GA. Steady-state plasma concentrations of diltiazem and its metabolites in patients and health

volunteers. Ther. Drug Monit. 18:40-45, 1996.

Klassen,G.A., Yeung, P.K.F., Barclay,K.D., Hung,O., Pollak,P.T., Buckley,S.: Gender differences in exercise and recovery blood pressure responses in normal volunteers given diltiazem. J. Clin. Pharmacol. 35: 1144-1149, 1995.

Yeung,P.K.F., Buckley,S.J., Cameron,R., Feng,J.D.Z., and Jordan,J.: Effect of phenobarbital pretreatment on the pharmacokinetics and metabolism of diltiazem in rats. Drug Metabolism and Interactions 13:29-39, 1996.

Tsui,B.C.H., Feng,J.D.Z., Buckley,S.J., and Yeung, P.K.F.: Pharmacokinetics and metabolism of diltiazem in rats following a single intra-arterial or single oral dose. Eur. J. Drug Met. Pharmacok. 19:369-373, 1994.

Klassen,GA, Yeung,PKF, Barclay,KD, Hung,OR, Pollak,PT, Buckley,SJ."Gender differences in diltiazem's action to lower blood pressure. Circ. 90(Pt 2): I-505, 1994.

Yeung,P.K.F., Mosher,S.J., and Landriault,H.: Effect of multiple doses of ranitidine on the pharmacokinetics and metabolism of diltiazem in dogs. Biopharm. Drug Disp. 15:207-215, 1994.

Yeung,P.K.F., Mosher,S.J., Li,R., Farmer,P.S., Klassen,G.A., Pollak,P.T., McMullen,M., and Ferrier,G.: Erythrocyte adenosine transport: A rapid screening test for cardiovascular drugs. J. Pharmacol. Meth. 30: 163-167, 1993.

Yeung,P.K.F., Chris,P., Haddad,C., Montague,T.J., McGregor,C., Quilliam,M.A., Xei,M., Li,R., Farmer,P., and Klassen,G.A.: Pharmacokinetics and metabolism of diltiazem in healthy males and females following a single oral dose. Eur. J. Drug Met. and Pharmacok., 18:199-206, 1993.

Yeung,P.K.F., Hubbard,J.W., Korchinski,E.D. and Midha,K.K.: Pharmacokinetics of chlorpromazine and key metabolites. Eur. J. Clin. Pharmacol., 45:563-569, 1993.

Li, R., Farmer,P.S., Xei,M., Quilliam,M.A., Pleasance, S., Howlett,S.E., and Yeung,P.K.F.: Synthesis, characterization and Ca antagonistic activity of diltiazem metabolites. J. Med. Chem. 35:3246-3253, 1992.

Yeung, PKF, Mosher,SH, and Pollak, PT,: High performance liquid chromatography assay for amlodipine: Application to stability and pharmacokinetic study in rabbits. J. Pharm. Biomed. Anal. 9:565-571, 1991.

Tsui,BCH, Mosher,SJ, and Yeung,PKF,: A reliable technique for chronic arterial catherization in the rat. J. Pharmacol. Methods 25:343-352,1991.

Yeung,PKF, Mosher,SJ, MacRae,DA, and Klassen,GA,: Effect of diltiazem and its metabolites on the uptake of adenosine in blood: An in vitro investigation. J. Pharm. Pharmacol.43:685-689, 1991.

Yeung,PKF, Mosher,SJ, Klassen,GA, McGilveray,IJ,: Stability of diltiazem and its metabolites in plasma during storage. Therap. Drug Monitoring 13:369-374,1991.

Yeung,PKF, Mosher,SJ, Pollak,PT,: Pharmacokinetics and metabolism of diltiazem in rabbits after a single intravenous or single oral administration. Eur.J.Drug Met.Pharmacok. 16: 69-74, 1991.

Yeung,PKF, Mosher,SJ, Quilliam,MA, and Montague,TJ,: Species comparison of pharmacokinetics and metabolism of diltiazem in humans, dogs, rabbits and rats. Drug metabolism Disp.18:1055-1059, 1990.

Yeung,PKF, Montague,TJ, Tsui,B, and McGregor,C,: High performance liquid chromatography assay of diltiazem and six of its metabolites: Application to a pharmacokinetic study in healthy volunteers. J. Pharm. Sci. 78:593-597, 1989.

Yeung,PKF, Hubbard,JW, Korchinski,ED, and Midha,KK,: Radioimmunoassay for the N-oxide metabolite of chlorpromzine in human plasma and its application to a pharmacokinetic study in healthy men. J. Pharm. Sci. 76:803-808, 1987.

Midha,KK, Hubbard,JW, Cooper,JK, Gurnsey,T, Hawes,EM, McKay,G, Chakraborty,BS, and Yeung,PKF,: Therapeutic monitoring of chlorpromazine IV: Comparison of a new high performance liquid chromatographic method with radioimmunoassay for parent drug and some of its major metabolites. Therap. Drug Monitoring 9:358-365, 1987.

McKay,G, Yeung,PKF, Qualtiere,L, and Midha,KK,: The use of monoclonal antibodies in drug analysis. In Briemer,DD, and Speiser,P,(eds): Topics in Pharmaceutical Sciences, Elsevier Science Publishers, Amersterdam, Netherland, 19-28, 1985.

Hawes,EM, Hubbard,JW, Martin,M, Mckay,G, Yeung,PKF, and Midha,KK,: Therapeutic monitoring of chlorpromazine III: Minimal interconversion between chlorpromazine and metabolites in human blood under physiological conditions. Therap. Drug Monitoring, 8: 37-41, 1986.

Yeung,PKF, Hubbard,JW, Baker,BW, Looker,MR, and Midha,KK,: Isotopic fractionation of 3Hmethyl- chlorpromazine and 3H-methyl-7-hydroxychlorpromazine by reversed-phase HPLC. J. Chromatogr. 303:412-416, 1984.

Yeung,PKF, Mackay,G, Ramshaw,IA, Hubbard,JW, and Midha,KK,: A comparison of two radioimmunoassays for 7-hydroxychlorpromazine: Rabbit polyclonal antibodies vs. mouse monclonal antibodies. J. Pharmacol. Exp. Therap. 233:816-822, 1985.

Yeung,PKF, and Midha,KK,: Analysis of chlorpromazine in plasma. In Sunshine,I.(ed): Methodology for Analytical Toxicology, Vol 3, CRC Press, Florida, U.S.A., 47-51, 1985.

Yeung,PKF, Hubbard,JW, Cooper,JK, and Midha,KK,: A study of the kinetics of chlorpromazine sulfoxide by a specific radioimmunoassay after a single oral dose of chlorpromazine in healthy volunteers. J. Pharmacol. Exp. Therap. 226:833-838, 1983.

Hall,K., Yeung,PKF, and Midha,KK,: Decomposition of sulfoxide metabolites of phenothiazine antipsychotics during gas chromatographic analysis. J Chromatogr. 231:200-204, 1982.

Midha,KK, Cooper,JK, Hawes,EM, Hubbard,JW, Roscoe,RMH, Shetty,HU, and Yeung,PKF,: Suitable analytical methods for bioequivalence of antipsychotic drugs. Psychopharmacol. Bull. 17:15-16, 1981.

Midha,KK, Hubbard,JW, Cooper,JK, Hawes,EM, Founier,S, and Yeung,PKF,: Radioimmunoassay for trifluoperazine in human plasma. Br. J. Clin. Pharmacol. 12:189-193, 1981.

Midha,KK, Mackonka,C, Cooper,JK, Hubbard,JW, and Yeung,PKF,: Radioimmunoassay for perphenazine in human plasma. Br. J. Clin. Pharmacol. 11:85-88, 1981.

Review Articles or book chapters

Mouris,J and Yeung,PKF (2005 Book Review). “Applied Clinical Pharmacokinetics” by Bauer, LA, 2001 Edition, McGraw-Hill, Toronto, Ont., Canada.

Yeung,PKF. Dp-b99. Current Opinion in Investigational Drugs, 5(1): 90 - 94, 2004. (Thompson’s Current Drug Database (Iddb), November 14th, 2003.)

Yeung PKF. GEM-231. Thompson’s Current Drug Database (Iddb), April, 2003 (Current Opinion In Molecular Therapeutics 5(3): 315 - 320, 2003.

Yeung,PKF. VEGF-2. Current Opinion in Investigational Drugs, 2(6): 796 - 800, 2001

Yeung,PKF. Motexafin Lutetium, Idrugs, 4(3): 351 - 359, 2001.

Yeung,PKF. Technology evaluation: Transgenic antithrombin III (rhAT-III), Genzyme Transgenics. Current Opinion in Molecular Therapeutics 2:(3):336-339, 2000.

Yeung,P.K.F. Pamiteplase. Current Opinion in Cardiovascular Pulmonary and Renal Investigational Drugs 1(1):171-174, 1999.

Yeung,PKF (Book Review): "Inhalation Toxicology: Research Methods, Applications and Evaluation. Salem,N(ed), Marcel Dekker Inc., 270 Madison Ave., N.Y.", CPJ 120:510, 1987.

McKay,G, Yeung,PKF, Qualtiere,L, and Midha,KK,: The use of monoclonal antibodies in drug analysis. In Briemer,DD, and Speiser,P,(eds): Topics in Pharmaceutical Sciences, Elsevier Science Publishers, Amersterdam, Netherland, 19-28, 1985.

Professional report (Peer Reviewed)

Yeung, PKF. A Meeting Report of the BIT’s 3rd Annual International Congress on Antibodies, Beijing, China, IDDB MEETING REPORT, March 23-25, 2011 (Thomson Reuters). Yeung, PKF. A meeting report of the Biomarker World Congress 2005, Philadelphia, PA, USA, 23- 25 May 2005. IDrugs 8(8): 625 – 628, 2005.

Yeung, PKF. A meeting report of the Eighth Annual Symposium of Canadian Society of Pharmaceutical Sciences (CSPS) “Accelerating Drug Discovery and Development” May 30 – June 2, 2005, Toronto, ON, Canada. Investigational Drugs Meeting Database, June, 2005, Thompson’s Current Drugs, London, UK.

Yeung, PKF. A meeting report of the Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists (AAPS), November 7 – 11, 2004, Investigational Drugs Meeting Database, November, 2004, Thompson’s Current Drugs, London, UK.

Yeung, PKF. A meeting report of the Annual Meeting and Symposium of the Canadian Soceity of Pharmaceutical Sciences (CSPS), 2004, June 9-12, Vancouver, BC, Canada, Investigational Drugs Meeting Database, June 2004, Thompson’s Current Drugs, London, UK

Yeung, PKF. A meeting report of the Annual Meeting and Symposium of the Canadian Society of Pharmaceutical Sciences (CSPS), May 28 - 31, 2003, Montreal, QC, Canada, Investigational Drugs Meeting Database, June, 2003, Thompson’s Current Drugs, London, UK

Yeung PKF. A meeting report for the Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists (AAPS), November 10 - 14, Toronto, Ontario, Canada., Investigational Drugs Meeting Database, November, 2002, London, UK. Idrugs 6(1): 12 - 15, 2003.

Yeung, PKF. A meeting report for the 5th Annual Symposium of Canadian Society of Pharmaceutical Sciences “New Technologies in Drug Discovery and Drug Development” June 13 – 15, 2002, Banff, Alberta, Canada. Investigational Drugs Weekly Highlights, July, 2002, London, UK.

Yeung, PKF. A meeting report for the Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists (AAPS) October 29 – November 2, 2000, Indianapolis, IN, U.S.A., Investigational Drugs Weekly Highlights, November, 2000, London, UK.

Yeung, PKF. A meeting report for the Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists (AAPS), November 14 - 18, 1999, New Orleans, LA, U.S.A., Investigational Drugs Weekly Highlights, December, 1999, London, UK.

Yeung, PKF. A meeting report for the 52nd Annual Meeting of the Canadian Cardiovascular Society October 19 - 23, 1999, Quebec City, QC, Canada, Investigational Drugs Weekly Highlights, November, 1999, London, UK.

Yeung, PKF. A meeting report for the Second Annual Symposium of Canadian Society of Pharmaceutical Sciences “Exploring Human Diversity in Drug Development & Pharmacotherapy”, Ottawa, Ontario, August 27 - 28, 1999, Investigational Drugs Weekly Highlights, September, 1999, London, UK.

Paper Presentations and Conference Abstracts

Starr, Laurie and Yeung, PKF. A rat model for study of cardiovascular toxicity of doxorubicin in vivo. Presented at the 4th Annual BHCRI Cancer Research Conference in Atlantic Canada, Halifax, NS, Canada, Nov 5 – 6, 2012.

Purcell, Chad and Yeung, PKF. Cardiovascular protective effect of diltiazem in a rat model of acute myocardial infraction with and without exercise pre-conditioning. Presented at the Nova Scotia College of Pharmacy Annual Research Event, Halifax, NS, Canada , October 21, 2012.

Yeung, PKF and Seeto, D. Diltiazem attenuates cardiovascular toxicities and reduces mortality induced by isoproterenol in a freely moving rat model in vivo. Presented at the Canadian Cardiovascular Congress, Toronto, ON, Canada October 27 – 31, 2012. (Presentation No 277).

Yeung, PKF and Seeto,D. Adenosine 5’-monophosphate concentration in red blood cell as potential surrogate biomarker for cardiovascular toxicity in rats in vivo. Presented at the Annual Symposium of the CSPS, Toronto, ON, Canada, June 12 – 15, 2012.

Li, Haijun, Zhang, Peicheng and Yeung, PKF. A simple and specific HPLC assay of Hydroxysafflor yellow A (HSYA) for pharmacokinetic studies in rats. Presented at the Annual Symposium of the CSPS, Toronto, ON, Canada, June 12 – 15, 2012.

Yeung, PKF. ATP metabolism as biomarker target for cardiovascular protection. Presented at the Atlantic Stroke Network Regional Scientific Meeting, Charlotte Town, PEI, July 29, 2011.

Li, H, Li, PY, and Yeung, PKF. A simple and specific HPLC assay of 20(S)-ginsenoside-Rg3 and Rh2 for pharmacokinetic studies in rats. Presented at the Annual Meeting and Symposium of AAPS, Washington, DC, USA, Oct 23 – 27, 2011.

Yeung, PKF and Seeto, D. Effect of isoproterenol on cardiovascular hemodynamics, RBC concentrations of adenine nucleotides, and mortality in a freely moving rat model in vivo. Presented at the Annual Meeting and Symposium of CSPS, Montreal, QC, Canada May 24-27, 2011.

Yeung, PKF and Seeto, D. Exercise pre-conditioning attenuates cardiovascular toxicities and reduces mortality induced by isoproterenol in a freely moving rat model in vivo. Presented at the Department of Medicine Research Day, Halifax, NS, Canada, April 21st, 2011 and also at the Annual Meeting and Symposium of CSPS, Montreal, QC, Canada May 24-27, 2011.

Yeung, PKF, Dauphinee, J, and Marcoux, T. Hemodynamic response to exercise and diltiazem in normotensive SD rats and SHR in vivo. Presented at the FIP Pharmaceutical Sciences 2010

World Congress in Association with the AAPS Annual Meeting and Exposition, New Orleans, LS, USA, November 14 – 18, 2010 (AAPS Journal 12(S2), 2010 W5392).

Yeung, PKF, Gouzoules, T, Dauphinee, J, and Marcoux, T. Effect of diltiazem on RBC concentrations of ATP in exercise model of SD rats and SHR in vivo. Presented at the FIP Pharmaceutical Sciences 2010 World Congress in Association with the AAPS Annual Meeting and Exposition, New Orleans, LS, USA, November 14 – 18, 2010 (AAPS Journal 12(S2), 2010 W5393).

MacDonald, CM, Shao, Di, Yeung, PKF, Agu, R. In vitro study of cardio-protective potential of anti-ischemic drugs against chemotherapy-induced cardiotoxicity. Presented at the Annual Cancer Symposium, Halifax, November 8 – 9, 2010.

Allain, BM, Grimms,J and Yeung, PKF. HPLC assay optimization for cladribine and anti-ischemia drugs. Presented at the College of Pharmacy Research Day, Halifax, September 14, 2010, and also at the Annual Cancer Symposium, Halifax, November 8 – 9, 2010.

Yeung, PKF, Dauphinee, J and Marcoux, T. Hemodynamic response to exercise in normotensive SD rats and SHR in vivo. Presented at the 13th Annual Symposium of the Canadian Society of Pharmaceutical Sciences, Vancouver, BC, Canada, June 2 – 5, 2010.

Yeung, PKF, Klein-Rygier, L, Dauphinee, J and Berman, JN. Effect of diltiazem on RBC concentrations of adenine nucleotides in zebrafish and restraining rat model in vivo. Pesented at the 13th Annual Symposium of the Canadian Society of Pharmaceutical Sciences, Vancouver, BC, Canada, June 2 – 5, 2010.

Yeung, PKF, Narayanan, S. Hemodynamic effects of single dose of cladribine in a rodent model. Presented at the 111th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics (ASCPT), Atlanta, Georgia, USA, March 17 – 20, 2010. Clin. Pharmacol. Ther. 87 (Supplement 1): S42, PII-10, 2010.

Yeung, PKF, Dauphinee, J, Gouzoules, T, and Simonson, K. Exercise improves hemodynamic profiles and increases RBC concentrations of ATP in a rodent model. Presented at the 111th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics (ASCPT), Atlanta, Georgia, USA, March 17 – 20, 2010. Clin. Pharmacol. Ther. 87 (Supplement 1): S42, PII-9, 2010.

Grimm, J, Klein, LC, Berman, JN, Marcoux, T., Yeung, PKF. Comparison of the pharmacokinetics of cladribine in rats and zebrafish following single and multiple doses. Presented at the College of Pharmacy Research Poster Day, Halifax, NS, Canada, September 17, 2009, and also at the Nova Scotia Cancer Research Symposium, Halifax, NS, Canada, November 16 – 17, 2009.

Yeung, PKF, Ding, L, Dauphinee, J. Pharmacokinetics and Hemodynamic effects of amlodipine in a rat model following repeated subcutaneous injections in vivo (BSR-10). Proceedings of the Annual Meeting of the Association of Faculties of Pharmacy of Canada, Halifax, NS, Canada, June 3 – 6, 2009; JPPS 13 (1): 10S, 2009.

Yeung, PKF, Klein-Rygier, L, Seibert, J, Dauphinee, J, Simonson, K and Berman, JN. Cladribine inhibits the effect of diltiazem to increase RBC concentrations of ATP in a zebrafish model (BSR-8). Proceedings of the Annual Meeting of the Association of Faculties of Pharmacy of Canada, Halifax, NS, Canada, June 3 – 6, 2009; JPPS 13 (1): 9S, 2009.

Yeung, PKF, Dauphinee, J, Simonson, K and Gouzoules, T. RBC concentrations of ATP as potential in vivo biomarkers for cardiovascular safety of anti-hypertensive agents in rats. Clin Pharmacol Ther 85 (Suppl 1): PIII-8, S70, 2009 (Proceedings of the Annual Meeting of the ASCPT, National Harbor (Washington DC), MD, USA, March 18 – 21, 2009) (Also presented at the Department of Medicine Research Day, Halifax, NS, Canada , April 9, 2009)

Klein-Rygier, L; Seibert, J; Dauphinee, J; Simonson, K, Yeung, PKF, and Berman, J. A pilot study using Danio rerio to evaluate the pharmacodynamics of nucleoside analogues and anti-ischemic agents in vivo, 23rd Annual Cameron Conference for Biology and Marine Biology Honours Students; Halifax, NS, Canada, March, 2009.

Yeung, PKF and Li, LM. Hemodynamic effects of diltiazem, losartan and amlodipine in a rat model following multiple doses in vivo. The IXth World Conference on Clinical Pharmacology and Therapeutics, Quebec City, QC, Canada, July 27 – August 1, 2008.

Yeung, PKF, Ghanem, A, Berman, J. Pharmacokinetics of cladribine and chitosan encapsulated cladribine in rats and zebrafish following a single dose (A38). Proceedings of the Annual Meeting of the Canadian Society of Pharmaceutical Sciences (CSPS), Banff, AB, Canada, May 22 – 25, 2008 Page 82.

Yeung, PKF, Howlett, J and Schindler, C. Effects of diltiazem on RBC concentrations of purine nucleotides in an exercise rat model following multiple doses in vivo. Annual Meeting of the American Society of Clinical Pharmacology and Therapeutics (ASCPT), Orlando, FL, USA, April 2 – 5, 2008. Clin Pharmacol Ther 83 (Suppl 1): S47 (PII –17), 2008.

Yeung, PKF and Howlett, J. Exercise hemodynamics and circulatory concentrations of purine nucleotides are sensitive biomarkers for assessing cardiovascular effects of diltiazem in a rat model in vivo. Dalhousie Department of Medicine Faculty Research Day, Halifax, Nova Scotia, Canada Nov 22, 2007.

Beaton, SD and Yeung, PKF. Plasma concentrations of adenosine and its oxypurine metabolites in rats following multiple doses of dipyridamole (A-39). Proceedings of the Annual Meeting of the Canadian Society of Pharmaceutical Sciences (CSPS), Banff, AB, Canada, May 22 – 25, 2008, Page 83. (College of Pharmacy Research Day, Dalhousie University, Halifax, Sept 20, 2007).

Yeung, PKF, Howlett, J, and Schindler, C. Exercise hemodynamic variables and RBC concentrations of purine nucleotides as sensitive biomarkers for cardiovascular drugs in a rat model in vivo. Presented at the Innovation in Clinical Trials: Implementation of Biomarkers, Toronto, ON, Canada, October 15 – 16, 2007.

Yeung, PKF, King, B, Narayanan, S, and Li, MLM. Pharmacokinetics of cladribine in plasma following intra-arterial and subcutaneous injections in a rat modelm (A-75, Page 111). Presented at the CSPS 10th Annual Symposium on Pharmaceutical Sciences, Montreal, QC, Canada, May 30 – June 2, 2007.

Yeung,PKF, Ding, L, and Li, MLM. Pharmacokinetics and Hemodynamic effects of losartan in a rat model following repeated subcutaneous injections in vivo. Presented at the CSPS 10th Annual Symposium on Pharmaceutical Sciences, Montreal, QC, Canada, May 30 – June 2, 2007.

Yeung, PKF, Li, MLM, Feng,JRJ, and Casley, WL. Plasma and RBC concentrations of adenosine and ATP and hemodynamic measurements in normotensive SD rats and spontaneously hypertensive rats (Pilot study). Presented at the Annual Meeting of the American Society of Clinical Pharmacology and Therapeutics, Anaheim, California on March 21 - 24, 2007. Clin Pharmacol Therp 81 (Suppl 1): S50 (PII – 6), 2007.

Amoako-Tuffour, M, Zhou,S, Yeung,PKF, Agu,R. Permeation of losartan across human tracheobronchial epithelium, Calu-3 cells. Presentation at the Annual College of Pharmacy Research Day, Dalhousie University, Halifax, NS, Canada, September 21, 2006.

King, B, Li, ML, Jaraar,A, Yeung, PKF. Plasma Concentrations Of Cladribine In Rats Following A Single Dose. Presentation at the Annual College of Pharmacy Research Day, Dalhousie University, Halifax, NS, Canada, September 21, 2006; and also at the Cancer Research Symposium, Halifax, Nov 10, 2006.

Yeung,PKF, Alcos,A, Tang,J, and Casley,WL. Pharmacokinetics and metabolism of diltiazem in normotensive and hypertesnive rat models following repeatedly subcutaneous injections in vivo. Presented at the Annual Meeting of the American Association of Pharmaceutical Scientists, San Antonio, TX, USA, October 29 – November 2nd, 2006. (The AAPS Journal. 2006; 8(52):W4358.)

Yeung, PKF, Jarrar,A, Ferguson,C, and Narayanan, S. A sensitive and specific HPLC assay of cladribine for pharmacokinetic studies in rats . Presented at the 9th Annual International Symposium on Pharmaceutical Sciences, Ottawa, Ontario, Canada, May 24 – 27, 2006, A-63, page 69 .

Yeung,PKF, Alcos,A, Tang, J, and Casley,WL. Hemodynamic effects of diltiazem in different rat models following repeated subcutaneous injections in vivo. Presented at the 9th Annual International Symposium on Pharmaceutical Sciences, Ottawa, Ontario, Canada, May 24 – 27, 2006, A-62, page 68.

Yeung,PKF, Alcos,A, Tang, J, and Tsui. Pharmacokinetics and hemodynamic effects of diltiazem in rats following single and repeated subcutaneous injection in vivo. Presented at the Annual Meeting of the ASCPT, Baltimore, MD, USA, Mar 8 – 11, 2006 (Clin Pharmacol Therap 79(2): P53 (PII-66).

Jaraar, A, Ferguson, C., Clark,J., Narayanan, P., Yeung, PKF. Development of a HPLC assay of cladribine and fludarabine for pharmacokinetic studies. Annual Cancer Research Symposium, Cancer Research Training Program, Halifax, Nova Scotia, Canada, November 9th, 2005.

Amoako-Tuffour, M, Agu, M, Yeung, PKF. HPLC assay for Losartan and EXP 3174 in culture fluid for the study of nasal absorption. Presented at the 7th Annual College of Pharmacy Research Day, Halifax, Nova Scotia, Canada, September 15, 2005.

Mouris, J., Yeung, PKF, Pinto, D, Chisholm, K. Mass Spectrometry Detection of Angiotensin II as a Biomarker for Cardiovascular Events in a Feasibility Study. Presented at the 7th Annual College of Pharmacy Research Day, Halifax, Nova Scotia, Canada, September 15, 2005.

Yeung, PKF. Development of targeted drug therapy. Presented at the Annual Meeting of the alhousie University Institute for Research in Materials, June 17, 2005.

Yeung, PKF, Stadnyk, A, Pinto, Dervand., and Pollak, PT. Biomarkers for anti-ischemic drugs. Presented at the Biomarkers World Congress, Philadelphia, PA, USA, May 23 – 25, 2005.

Yeung, PKF, Alcos, A, Tang, J, and Tsui, Ban. Hemodyanmic effects of diltiazem in rats following single and repeated subcutaneous injection in vivo. Presented at the 8th Annual Symposium of the Canadian Society of Pharmaceutical Sciences, Toronto, Ontario, Canada, May 30 – June 2, 2005.

Yeung, PKF; Feng, J, and Fice, D. Pharmacodynamic interactions between diltiazem and adenosine in rabbits in vivo. AAPS Journal. 2004; 6(S1):(R-6213). Presented at the Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists, Baltimore, MD, USA. Nov 7 – 11, 2004.

Yeung. PKF. Biomarkers for myocardial ischemia and stroke. Presented at the Atlantic Regional Linkages in Stroke Research., Dalhousie University, Halifax, Nova Scotia, September 16, 2004

Ferguson, C, Clark, J and Yeung, PKF. Development of a HPLC assay of cladribine for pharmacokinetic studies. 6th Annual Report and Poster Session of Summer Studentship Projects, College of Pharmacy, Dalhousie University, NS, Canada, Sept 28, 2004.

Yeung, PKF, Feng, J, Fice, D. Effect of diltiazem on the hemodynamic response to adenosine in vivo. Presented at the 7th Annual Symposium of the Canadian Society of Pharmaceutical Sciences, Vancouver, BC, Canada, June 9 – 12, 2004.

Clark,J and Yeung, PKF. A feasibility study to develop HPLC assay for nucleoside anti-cancer agents for pharmacokinetic studies. Presented at the Annual Cancer Research Symposium, Dalhousie University, Halifax, Nova Scotia, Canada, November 5, 2003, p 34 (A-24), and also at the 7th Annual Symposium of the Canadian Society of Pharmaceutical Sciences, Vancouver, BC, Canada, June 9 – 12, 2004.

Yeung, PKF, Feng,JDZ and Fice, Debra. Adenine nucleotides as in vivo biomarkers for antiischemic drugs. Presented at the 12th North American ISSX Meeting, Providence, RI, USA October 12 - 16, 2003 (Drug Metabolism Reviews 35(2): 163 (A-326), 2003)

Yeung, PKF, Feng, JDZ and Fice,D. Effect of diltiazem and losartan on RBC concentrations of adenine nucleotides. Presented at the Annual Symposium (6th) of the Canadian Society of Pharmaceutical Sciences, Montreal, Qubec, Canada, May 28 - 31, 2003.

Yeung, PKF, Feng,JDZ and Fice,D. Rbc Adenine Nucleotides As Potential Therapeutic Markers For Anti-Ischemic Drugs. Presented at the Annual Meeting and Exposition of the American Association of Pharmacuetical Scientists, Toronto, Ontario, Canada, Nov 10 - 14, 2002. (AAPSPharm Sci., Vol. 4, No. 4, Abstract W5258 ,2002)

Samson, Pierre, and Yeung, P.K.F. Genetic polymorphism of UDP-glucuronosyltransferase (UGT1A!) As a marker for drug selection and dosage optimization (A-11). Presented at the 4^th Annual Report & Poster Session of Summer Studentship projects, Sept 17, 2002. College of Pharmacy, Dalhousie University, Halifax, NS, Canada .

Yeung, P. K.F., Feng, JDZ, Fice, Debbie, and Jarvis,A. Hemodynamic and neurohormone effects of diltiazem in rats. 5th Annual Symposium of the Canadian Society Pharmaceutical Sciences, June 13 - 15, 2002, Banff, Alta, Canada.

Sears, Melanie and Yeung, P.K.F. Pharmacokinetics, pharmacogenetics and metabolism of warfarin. (Abs 14). Third annal report and poster session of summer studentship project, College of Pharmacy, Dalhousie University, Halifax, NS, Canada, Oct 2, 2001

Yeung, P. K.F., Feng, Joe D.Z., Fice Debbra. Hemodynamic effect of adenosine and its modulation by diltiazem in rabbits. Canadian Cariovascular Congress, Halifax, Nova Scotia, Canada. Oct 20 - 24, 2001. Can. J. Cardiol. 17 (Suppl C), A-288, 2001.

Yeung, P. K.F., Feng, Joe D.Z., Fice, Debbra. Modulation of the hemodynamic effect of adenosine by diltiazem in rabbits. Canadian Cariovascular Congress, Halifax, Nova Scotia, Canada. Oct 20 - 24, 2001. Can. J. Cardiol. 17 (Suppl C), A-296, 2001.

Yeung,P. K.F., Jarvis,Angela and Feng, Joe D.Z. Effect of losartan on heart rate and blood pressure response to exercise in rat (A-2). 4th Annual Symposium of the Canadian Society for Pharmaceutical Sciences, Ottawa, Ontario, Canada, June 14 - 16, 2001. (J. Pharm. Pharm. Sci. 4 (2):115, 2001).

Yeung, P. K.F. , Jamieson, Angela, Smith, Gareth J, Pollak, P. Timothy. A reversed phase HPLC assay for losartan and its active metabolite EXP3174 in plasma (A-1). 4th Annual Symposium of the Canadian Society for Pharmaceutical Sciences, Ottawa, Ontario, Canada, June 14 - 16, 2001 (J. Pharm. Pharm. Sci. 4 (2):115, 2001).

Richard, ME, Jarvis,A, Wilson,JA and Yeung,PKF. Development of a Chiral HPLC Assay for Warfarin in Plasma (A-14). Dalhousie University College of Pharmacy Second Annual Summer Student Poster Session, Halifax, Nova Scotia, Canada, Sept 26, 2000.

Yeung,PKF, Feng,JDZ, and Jarvis,A. Hemodynamic effects of losartan in rats during exercise. Presented at the Annual AAPS Meeting (Oct 29 - Nov 2, 2000, Indianapolis, Indiana, USA). Yeung,PKF, Feng,JDZ, and Jarvis,A. Effect of diltiazem on plasma concentration of adenosine and its oxypurine metabolites in rats during exercise. Proceedings of the Annual Meeting of the Association of Faculty of Pharmacy of Canada, Saskatoon, Saskatchewan, Canada, June 24 - 26, 2000.

Yeung,PKF, Feng,JDZ, Fice,D and Jarvis,A. : Hemodynamic and neurohormone effects of cardiac drugs. Department of Medicine Research Day, Dalhousie University, Halifax, Nova Scotia, May 4, 2000 (Proceedings A-25, page 19).

Covert TJ, Wilson,J, Yeung,PKF,: Development of a warfarin assay using high performance liquid chromatography (HPLC) for pharmacokinetic and pharmacodynamic studies. Presented at the Annual College of Pharmacy Poster Research Day, Dalhousie University, Halifax, September 28, 1999.

Yeung,PKF, Feng,JDZ, and Fice,D,: Hemodynamic and neurohormone effects of diltiazem in rat during exercise. Presented at the Annual Meeting of the American Association of Pharmaceutical Scientists, New Orleans, LA, USA, Nov 14 - 18, 1999 ( AAPS PharmScism Suppl. 1:S-598, A-4005, 1999).

Yeung,PKF, Jamieson,A, Smith,GJ, Fice,D, and Pollak,PT,: A simple HPLC assay for losartan and its active metabolite EXP3174 in human plasma. Presented at the Annual Meeting of the American Association of Pharmaceutical Scientists, New Orleans, LA, USA, Nov 14 - 18, 1999 (AAPS PharmScism Suppl. 1:S-34, A-1114, 1999).

Yeung,PKF, Klassen,GA, Pollak,PT, Hung,OR, Farmer,PS, and Quilliam, MA. “Pharmacokinetics and metabolism of diltiazem: What is the point?” Presented at the Annual Meeting of the Canadian Society of Pharmaceutical Sciences, Montreal, PC, Canada, Aug 27 - 28, 1999. J. Pharm. Pharm. Sci. 2:62-83, 1999.

Yeung,PKF, Feng,J, and Fice, D. “Hemodynamic effect of adenosine in rabbits”. Proceedings of the Annual Meeting of the AFPC/CCCP, Quebec City, QC, Canada June 10 - 13, 1999, A-32.

Yeung,PKF, Feng,JDZ, and Fice,D. “Modulation of hemodynamic effect of adenosine by diltiazem in rabbits”. Proceddings of the Annual Meeting of the AFPC/CCCP, Quebec City, QC, Canada June 10 - 13, 1999, A-31.

Yeung,PKF, Feng,JDZ, and Klassen,GA. APharmacokinetics and pharmacodynamics of diltiazem: Species differences.@ PharmSci Tm Suppl. 1: S-669,, 1998.

Yeung, PKF and Feng,JDZ. A Potential surrogate markers for pharmacodynamics of diltiazem: RBC concentrations of adenosine and adenine nucleotides.@ PharmSciTm Suppl. 1: S-329, 1998.

Yeung, PKF, Hung,OR, Pollak,PT and Klassen,GA. APharmacokinetics and haemodynamic effects of diltiazem in healthy volunteers at steady-state: Resting vs treadmill exercise@. PharmSciTm Suppl. 1: S-147, 1998.

Yeung,PKF, Feng,JDZ. "Effect of diltiazem on plasma and RBC concentrations of adenosine and oxypurine metabolites in rats". Proceeding of the Annual Meeting of the Association of Faculties of Pharmacy of Canada, St. John's, Newfoundland, May 24 - 26, 1998, BS8, pp5.

Yeung,PKF, Feng,JDZ, Buckley,SJ. "Pharmacokinetics and metabolism of diltiazem: comparing it to its metabolites in rabbits". The Annual Meeting of the Dalhousie University Department of Medicine Research Day, Halifax, NS, Canada, May 7, 1998.

Yeung,PKF, Feng,JDZ, Buckley,SJ."Pharmacokinetics and haemodynamic effect of diltiazem in rabbits: Effects of phenobarbital". The Annual Meeting of the American Association of Pharmaceutical Scientists, Boston, MA, U.S.A., Nov 2 - 6, 1997.

Tsui,BCH, Feng,JDZ, Yeung,PKF. "Pharmacokinetics and haemodynamic effect of diltiazem in rats: Effect of route of administration". The Annual Meeting of the American Association of Pharmaceutical Scientists, Boston, MA, U.S.A., Nov 2 - 6, 1997.

Yeung,PKF, Feng,JDZ, Buckley,SJ. "Pharmacokinetics and haemodynamic effect of diltiazem in rabbits: Comparing diltiazem to its major metabolites". The Annual Meeting of the American Association of Pharmaceutical Scientists, Boston, MA, U.S.A., Nov 2 - 6, 1997.

Yeung,PKF, Farmer,PS, Pollak,PT, and Verotta,D. "Pharmacokinetics and metabolism of diltiazem: Significance of metabolites". The Impact of Pharmacokinetics in Modern Drug Development: A Symposium Celebrating the Work and 60th Birthday of Dr. Leslie Z. Benet, San Francisco, CA, U.S.A., May 16 - 17, 1997.

Yeung,PKF, Feng,JDZ, and Buckley,SJ. "Pharmacokinetics and haemodynamic effects of diltiazem metabolites in rabbits". The Annual Department of Medicine Research Day, Dalhousie University, Halifax, Nova Scotia, Canada, May 1st, 1997.

Yeung,PKF, Feng,JDZ, and Buckley,SJ. "Pharmacokinetics and haemodynamic effect of two major metabolites of diltiazem in rabbits". The 7th North American Meeting of the International Society of Study of Xenobiotics (ISSX), San Diego, CA, USA, October 20-24, 1996.

Buckley,SJ, and Yeung,PKF. "An exercise animal model using the Sprague Dawley rat for pharmacokinetic and pharmacodynamic studies of cardiovascular drugs". The 7th North American Meeting of the International Society of Study of Xenobiotics (ISSX), San Diego, CA, USA , October 20-24, 1996.

Buckley,SJ, and Yeung, PKF. "Gender differences in the pharmacokinetics and pharmacodynamics of diltiazem in Sprague Dawley rats during treadmill exercise." The 7th North American Meeting of the International Society of Study of Xenobiotics (ISSX), San Diego, CA, USA, October 20-24, 1996.

Wang,Y and Yeung,PKF. "A simple and rapid high performance liquid chromatography assay with electrochemical detection for measurement of serotonin (5-HT) and 5-hydroxyindoleacetic acid (5- HIAA) in rat plasma". The 7th North American Meeting of the International Society of Study of Xenobiotics (ISSX), San Diego, CA, USA, October 20-24, 1996.

Wang,Y and Yeung,PKF. "Analysis of 3,4-dihydroxyphenylacetic acid (DOPAC), norepinephrine (NE), epinephrine (E) and dopamine (DA) in rat plasma by high performance liquid chromatography with electrochemical detection". The 7th North American Meeting of the International Society of Study of Xenobiotics (ISSX), San Diego, CA, USA , October 20-24, 1996.

Yeung,PKF, Feng,J, Buckley,SJ, Hung,OR, Pollak,PT, Barclay,KD, Klassen,GA. "Effect of diltiazem on adenosine metabolism in humans". Annual Meeting of the Association of Faculties of Pharmacy of Canada, Calgary, Alta, Canada. May 26-28, 1996.

Yeung,PKF, Feng,J, Buckley,SJ, Pollak,PT, Hung,OR, Barclay,KD, and Klassen,GA. "Effect of diltiazem on plasma concentrations of purine metabolites." Annual Meeting of the Dalhousie University Department of Medicine Research Day, Halifax, N.S., Canada, May 2, 1996 Yeung,PKF, Buckley,SJ and Feng,JD (Spon: G. Klassen). "Effect of losartan and its acidic metabolites on the uptake of 3H-adenosine by erythrocytes". FASEB J. 10:A433, 1996.

Pollak,PT, Veldhuyzen van Zanten,SJO, Kapoor,H, Yeung,PKF. "Pharmacokinetic modelling of omeprazole effects on the secretion of intravenous metronidazole from plasma into gastric fluid". Clin Invest. Med. 18: August, B51, 1995.

Yeung,PKF, Buckley,SJ, and Feng,JDZ. "Pharmacokinetics and metabolism of deacetyl Nmonodesmethyldiltiazem (M2) in rabbits after a single intra-arterial administration". Annual Meeting of the American Association of Pharmaceutical Scientists, Miami, FL, U.S.A., Nov 5-9, 1995.

Yeung,PKF, Feng,JDZ, and Buckley,SJ. "High performance liquid chromatography assay of adenosine, adenine nucleotides, and their purine metabolites in plasma and erythrocytes". Annual Meeting of the American Association of Pharmaceutical Scientists, Miami, FL, U.S.A., Nov 5-9, 1995.

Yeung,PKF, Feng,JDZ, Buckley,SJ and Klassen,GA. "Determination of adenosine and its metabolites in plasma by high performance liquid chromatography assay". Annual Meeting of the Association of Faculties of Pharmacy of Canada, Montreal, QC, Canada May 10 - 13, 1995.

Veldhuyzen van Zanten, SJO, Pollak, PT, Kapoor,H, and Yeung, PKF. "Pharmacokinetic modelling of the effects of omeprazole on secretion of intravenous metronidazole into gastric fluid. VIII th International Workshop on Gastroduodenal Pathology and Helicobacter pylori, Edinburgh, Scotland, July 7-9th, 1995.

Yeung,PKF, Klassen,GA, Buckley,SJ, and Feng,J. "Stability of adenosine in venous and arterial plasma during storage". Annual Department of Medicine Research Days, Dalhousie University, Halifax, NS, Canada May 4, 1995.

van Zanten, SJOV, Pollak,PT, Kapoor,H and Yeung, PKF. "Assessment of the effects of omeprazole on the secretion of intravenous metronidazole into gastric fluid using pharmacokinetic modelling". Annual Department of Medicine Research Days, Dalhousie University, Halifax, May 4- 5, 1995.

Yeung,PKF, van Zanten,SV, Little,R, Kapoor,H, Jordan,J, and Jiang,YQ."Determination of metronidazole and omeprazole concentrations in plasma and gastric fluid by HPLC. Presented at the 9th Annual Meeting of the American Association of Pharmaceutical Scientists (AAPS), San Diego, California, U.S.A., Nov. 6 - 10, 1994.

Yeung,PKF, Buckley,SJ, and Feng,JDZ."Pharmacokinetics and metabolism of deacetyl diltiazem (M1) in rabbits after a single intra-arterial administration". Presented at the 9th Annual Meeting of the American Association of Pharmaceutical Scientists (AAPS), San Diego, California, U.S.A., Nov. 6 - 10, 1994.

Yeung,PKF, Buckley,SJ, Kingemanse,J, and Pedder,SCJ. "A simple high performance liquid chromatography assay for 3,4-dihydroxyphenyl glycol in human plasma" Presented at the 9th Annual Meeting of the American Association of Pharmaceutical Scientists (AAPS), San Diego, California, U.S.A., Nov. 6 - 10, 1994.

Yeung,PKF, Montague,T, Klassen,GA, Farmer,PS, Quilliam,MA, Pollak,PT, and Hung,O."Pharmacokinetics, metabolism and pharmacodynamics of diltiazem. Presented at the 10^th International Symposium on Microsomes and Drug Oxidation. Toronto, Ont., Canada. July 18 - 21, 1994.

Kapoor,H, Yeung,PK, Pollak,PT, van Zanten,SJV,: The effect of omeprazole on the secretion of intravenously administered metronidazole (MET) into gastric juice. Helicobacter Pylori: Beginning the second decade, Houston, Texas, Sept. 30 - Oct. 1, 1994.

Yeung,PKF, Klassen,GA, Mosher,SJ, Feng,J, and Jordan,J,: Improved high performance liquid chromatography assay for diltiazem and seven of its metabolites in human plasma. Presented at the Department of Medicine Research Day, Dalhousie University, Halifax, N.S., Canada. May 5-6, 1994.

Kapoor,H., Little,R., Yeung,PKF., Pollak,PT., van Zanten,SJ.,:Secretion of intravenously administered metronidazole into gastric juice. A rational antibiotic for treatment of Helicobacter Pylori. Presented at the Department of Medicine Research Day, Dalhousie University, Halifax, N.S., Canada. May 5-6, 1994.

Yeung,PKF, van Zanten,SV, Kapoor,H, Little,R, Jordan,J, Jiang,YQ,: High performance liquid chromatography assay for metronidazole and omeprazole in plasma and gastric fluid. Presented at the Department of Medicine Research Day, Dalhousie University, Halifax, N.S., Canada. May 5 - 6, 1994.

Liu Y, Li R, Farmer PS, Yeung PKF, Quilliam MA. Enantiomerically pure metabolites of diltiazem. 207th ACS National Meeting, Med Chem Abstr 264, Mar 13-17, 1994, San Diego, CA, U.S.A.

Yeung,PKF, Mosher,SJ, Cameron,R, and Jordan,J. Effect of phenobarbital pre-treatment on the pharmacokinetics and metabolism of diltiazem in rats. Presented at the 8th Annual Meeting & Exposition of the American Association of Pharmaceutical Scientists (AAPS), Orlando, FL, U.S.A., Nov 14-18, 1993.

Tsui,BCH, Mosher,SJ, and Yeung,PKF. Effect of route of administration on pharmacokinetics and metabolism of diltiazem in rats. Presented at the Association of Faculties of Pharmacy of Canada (AFPC) Biotechnology Conference, Vancouver, B.C., Canada, July 31 - Aug 4, 1993.

Yeung PKF, Klassen,GA, Mosher,SJ, Orlando,H, Barclay,KD, Pollak,PT, Li,R, Feng,J and Farmer,PS. Steady-state plasma concentrations of diltiazem and its metabolites in healthy males and females. Presented at the Annual Department of Medicine Research Day, Dalhousie University, Halifax, N.S., Canada, May 6-7, 1993.

Barclay,KD, Klassen,GA, Yeung,PKF, Mosher,SJ, Pollak,PT, Feng,J and Hung,OR. Gender differences in the response to exercise before and after diltiazem. The FASEB Journal 7:P A250, 1993.

Klassen GA, Yeung PKF, Hung OR, Pollak PT, Barclay KD, Mosher SJ. Should gender differences guide therapeutics. J. Am. Coll. Cardiol. 21(Suppl A): A58, 1993.

Yeung PKF, Mosher SJ and Landriault H : Effect of ranitidine on the pharmacokinetics and metabolism of sustained-released diltiazem in dogs. Presented at the 4th North American ISSX meeting, Bal Harbour, Florida, U.S.A., November 2 - 6, 1992.

Yeung PKF, Klassen GA, Mosher SJ, Hung O, Barclay KD, Pollak PT, Li R, Feng J, and Farmer PS: Pharmacokinetics and pharmacodynamics of diltiazem and its metabolites during exercise stress test in healthy males and females. Presented at the 7th Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists, San Antionio, TX, U.S.A., November 15-19, 1992.

Tsui BCH and Yeung PKF: Regression modeling of pharmacokinetic and pharmacodynamics relationship of diltiazem and its metabolites. Presented at the 35th Annual Meeting of the Canadian Federation of Biological Societies, Victoria, B.C., June 18-20, 1992.

Feng,DZ, Mosher,SJ, Klassen GA, Yeung PKF (Spon: Renton KW): High performance liquid chromatography assay for adenosine and other purine metabolites in human plasma (A-237). Presented at the 35th Annual Meeting of the Canadian Federation of Biological Societies, Victoria, B.C., June 18-20, 1992.

Gardner M., Kimber S., Yeung PKF., Klassen G,: Acute angiotensin converting enzyme (ACE) inhibition does not inhibit inducible ventricular tachycardia in man. Submitted for consideration to be presented at the Canadian Cardiovascular Society Meeting, Ottawa, Ontario, Canada. October 20- 24, 1992.

Midha KK, Hubbard JW, Yeung PKF, Ormsby E, McKay G, Hawes EM, Korchinski ED, Gurnsey T, Rawson M, and Schwede R,: Bioequivalence of highly variable drugs I. Application of replicate design. Presented at the Bio-International'92. Bioavailability Bioequivalence and Pharmacokinetic Studies Conference. Bad Homburg/Frankfurt, Germany, May 20-22, 1992.

Yeung PKF, Mosher SJ, and Klassen GA,: Effect of calcium antagonists on the uptake of adenosine in blood. Presented at the Annual Meeting of the Association of Faculties of Pharmacy of Canada, Winnipeg, Man., May 16-20, 1992.

DeLorey LM, Bain CA, Yeung PKF, and Mosher SJ,: Determination of serum and gingival drug levels following localized minocycline application. Presented at the IADR General Session and Exhibition, Glasgow, Scotland, July 1-4, 1992.

Yeung PKF, Mosher SJ, Pedder SCJ, and DeLorey L,: High performance liquid chromatography assay for minocycline in gingival fluid and plasma. Presented at the 6th Annual Meeting of the American Association of Pharmaceutical Scientists, Washington, DC, November 1991.

Yeung PKF, Mosher SJ, Klassen GA and McGilveray IJ,: Stability of diltiazem and major metabolites in spiked vs incurred (volunteer) plasma. Presented at the 6th Annual Meeting of the American Association of Pharmaceutical Scientists, Washington, DC, November 1991.

Li R, Farmer PS, Xei M, Quilliam MA and Yeung PKF, : Synthesis and characterization of diltiazem metabolites. Presented at the 202nd American Chemical Society National Meeting, New York City, NY, U.S.A., August 26-30, 1991.

Yeung PKF, Prescott C, Haddad C, Marshall D, Tremayne H, McGregor C, Quilliam MA, and Montague TJ,: Pharmacokinetics and metabolism of diltiazem in healthy volunteers following a single oral dose. Presented at the 3rd International ISSX meeting, Amsterdam, The Netherlands, June 24-28, 1991.

Xie,M, Yeung,PKF. Farmer,P, Li,RS, Quilliam,MA and Pleasance,S,: Analysis of diltiazem and its metabolites by combined HPLC and mass spectrometry. Presented at the Annual Meeting of the Association of Faculties of Pharmacy of Canada (AFPC), St. John's, Newfoundland, May 24-28, 1991.

Tsui, BCH, Mosher,SJ, Yeung PKF,: An economical halothane anaesthetic device and a reliable technique for chronic carotid arterial catherization in the rat. Presented at the Annual Meeting of the Association of Faculties of Pharmacy of Canada (AFPC), St. John's, Newfoundland, May 24-28, 1991.

Pollak,PT, Bryden,K., Mosher,SJ, and Yeung, PKF: Amidodarone assay by high performance liquid chromatography with trifluoperizine internal standard and solid-phase extraction. Presented at the 3rd International Symposium on Pharmaceutical and Biomedical Analysis. Massachusetts, U.S.A., April, 1991.

Yeung, PKF, Mosher,SJ, and Klassen, GA: High performance liquid chromatography assay for adenosine and its metabolites. Presented at the Department of Medicine Research Day, Dalhousie University, Halifax, Nova Scotia, May, 1991.

Yeung,PKF, Mosher,SJ, and Pollak,T: High performance liquid chromatography assay for amlodipine: Application to stability and pharmacokinetic study. Presented at the 5th Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists, Las Vegas, Nevada, U.S.A., November 4-8, 1990.

Yeung,PKF, Mosher,SJ, MaCrae,DA, and Klassen,GA: Effect of diltiazem and its metabolites on the uptake/metabolism of adenosine in blood: An in vitro investigation. Presented at the 5th Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists, Las Vegas, Nevada, U.S.A., November 4-8, 1990.

Yeung,PKF, Mosher,SJ, and Meisner,P,: Pharmacokinetics and metabolism of diltiazem in dogs following a single intravenous, single and multiple oral doses of diltiazem. Presented at the 73rd CIC meeting, Halifax, July 1990.

Mosher, SJ, Klassen,GA, and Yeung,PKF,: The rabbit as a useful animal model for studying the pharmacokinetics of calcium antagonists. Presented at the 29th Annual Convention of Canadian Association of Laboratory Animal Sciences (CALAS) meeting, Halifax, July 1990.

Quilliam,MA, Pleasance,S, Xie,M, and Yeung,PKF,: Liquid chromatorgraphy-tandem mass spectrometry for the analysis of drugs and metabolites. Presented at the Annual Meeting of the American Society of Mass Spectrometry, Arizona, U.S.A., June 1990.

Kimber,S, Yeung,PKF, Johnstone,D, Klassen,G, and Gardner,M,: Enalaprilat and ventricular tachycardia-preliminary experience. Presented at the Annual Department of Medicine Research Day, Dalhousie University, Halifax, May 1990.

Yeung,PKF, Mosher,SJ, MacRae,DA, Klassen,GA,: Effect of calcium antagonists on the uptake/metabolism of adenosine in blood: An in vitro study. Presented at the Annual Department of Medicine Research Day, Dalhousie University, Halifax, May 1990.

Yeung,PKF and Mosher,SJ,: Pharmacokinetics and metabolism of diltiazem in rabbits after a single intravenous or single oral administration. Presented at the Annual Meeting of the Association of Faculties of Pharmacy of Canada, Regina, May 1990.

Pleasance, S, Mei,X, Quilliam,MA, and Yeung,PKF,: Analysis of diltiazem and its metabolites by combined liquid chromatogragphy/tandem mass spectrometry. Presented at the 6th Montreux Symposium on Liquid Chromatography Mass Spectrometry, Ithaca, N.Y., U.S.A., July 1989. Yeung,PKF, Mosher,SJ, Quilliam,MA, and Montague,TJ,(Spon: KW Renton): Species comparison of diltiazem pharmacokinetics and metabolism in man, dog, rabbit and rat. Presented at the 32^nd Annual Meeting of the Canadian Federation of Biological Societies, Calgary, Canada, June 1989.

Yeung,PKF, Mosher,SJ, Quilliam,MA, and Montague,TJ,: Pharmacokinetics and metabolism of diltiazem in man. Presented at the Department of Medicine Research Day, Dalhousie University, Halifax, N.S., Canada, May 1989.

Yeung,PKF, Montague,TJ, Tsui,B, and McGregor,C,: High performance liquid chromatography assay of diltiazem and six of its metabolites in plasma of healthy volunteers. Presented at the 3^rd Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists, Orlando, Florida, October 1988.

Yeung,PKF, Montague,TJ, Tsui,B, and Hooper,DL,: Synthesis and characterization of a hapten and its bovine serum albumin conjugate for diltiazem. Presented at the Annual Meeting of the Association of Faculties of Pharmacy of Canada, Saint John, N.B., May 1988.

Yeung,PKF, Montague,TJ, Prescott,C, Haddad,C, Marshall,D, Tremayne,H, McGregor,C,: Plasma concentrations of diltiazem and its metabolites in man. Presented at the Department of Medicine Research Day, Dalhousie University, Halifax, May 1988.

Yeung,PKF, Hubbard,JW, Gurnsey,T., and Midha,KK,: Radioimmunoassay for 7- hydroxychlorpromazine: Monoclonal vs polyclonal antibodies and comparison with HPLC. Presented at the "Toxicology Research Day", Dalhousie University, Halifax, NS, Canada, 1987.

Yeung,PKF, Wallace,SM, Hubbard,JW, and Midha,KK,: Plasma concentrations of chlorpromazine and major metabolites in human volunteers. Presented at the Annual Meeting of the Association of Faculties of Pharmacy of Canada, Quebec City, May, 1986.

Yeung,PKF, Hubbard,JW, and Midha,KK,: Radioimmunoassay for the N-oxide metabolite of chlorpromazine in human plasma. Presented at the 45th International Congress of Pharmaceutical Sciences, Montreal, Canada, September 1985.

Yeung,PKF, Mackay,G, Ramshaw,IA, Hubbard,JW, and Midha,KK,: A comparison of two radioimmunoassays for 7-hydroxychlorpromazine: Rabbit polyclonal antibodies vs. mouse monoclonal antibodies. Presented at the 131st Annual Meeting of the Academy of Pharmaceutical Association, Montreal, Canada, May 1984.

Yeung,PKF, Hubbard,JW, Cooper,JK, and Midha,KK,: Determination of plasma chlorpromazine sulfoxide concentration by a specific radioimmunoassay. Presented at the 26th Annual Meeting of the Canadian Federation of Biological Societies, Ottawa, Canada, June 1983.

Invited Paper Presentation:

Yeung PKF. “From chlorpromazine to adenosine : How did it happen?” Presented at the Faculty of Pharmacy, University of Manitoba, Winnipeg, MB, Canada, Oct 24, 2012.

Yeung, PKF. “ATP metabolism as biomarker target for cardiovascular homeostasis” Presented at the Target’s 2nd World Cardiovascular, Diabetes, and Obesity Online Conference, September 11 – 14, 2012.

Yeung, PKF. “ATP metabolism as biomarker target for drug development” Presented at the Annual Symposium of the CSPS, Toronto, ON, Canada, June 12 – 15, 2012.

Yeung, PKF. “Bioavailability and bioequivalence: Concept and applications”. Presented at the Inspectorate, Health Canada, Ottawa, ON, Canada, November, 27th, 2009.

Yeung, PKF, Dauphinee, J, Simonson, K, Beaton, S and Gouzoules, T, “ATP and adenosine as biomarkers for drug development”. Presented at the 2nd World Conference on Magic Bullets (Ehrlich II), Nuremberg, Germany, October 3 – 5, 2008.

Yeung, PKF, “Cross-Professional Collaboration: The Future of Health Research?” Panel presentation at the Interdisciplinary Health Sciences Research Day, Dalhousie University, Halifax, Nova Scotia, Canada, February 7, 2007.

Yeung, PKF, “Biomarkers for ischemic heart disease”. Presented at MedMira Laboratories, Halifax, Nova Scotia, Canada, October 24, 2006.

Yeung, PKF, “Pharmacokinetics, Metabolism and Biomarkers for Anti-ischemic Drugs”. Presented at the Department of Biomedical Engineering, Dalhousie University, Halifax, Nova Scotia, Canada, December 1, 2005.

Yeung,PKF, “Biomarkers for target development – Opportunities and challenges”. Presented at the Department of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada, November 3rd, 2005.

Yeung, PKF, “ Biomarkers for targeted therapy – Opportunities and challenges for the medical diagnostic industry”. Presented at the MedMira Laboratory Inc., Halifax, Nova Scotia, Canada, Sept 21, 2005.

Yeung, PKF, “Biomarkers for targeted therapy – Opportunities, challenges, and what else?” Presented at a Multidisciplinary Oncology Grand Round, Captial Health/QEII HSC Cancer Care Program, Halifax, Nova Scotia, Canada, September 8, 2005.

Yeung, PKF, “Biomarkers for anti-ischemic drugs – A drugist’s perspective. Presented at the Heart and Stroke Foundation of Nova Scotia Reception, Windsor, Nova Scotia, Canada, April 27, 2005.

Yeung, PKF, “Biomarkers for targeted drug and drug therapy”. Presented at GSK, Toronto, Ontario, Canada, Oct 19, 2004.

Yeung, PKF, “Biomarkers for Vascular Health”. Presented to the Neurology Group of the Halifax Infirmary, Capitol District Health Authority, Halifax, Nova Scotia, Canada, July 23, 2004.

Yeung, PKF. “Potentials And Challenges Of Applying Biomarker Approach To Drug Development”. Presented at the 2004 LabFusion Meeting in Boston, MA, USA, June 12 – 16, 2004.

Yeung, PKF, “Biomarkers for pre-clinical and clinical development of anti-cancer drugs”, Pediatric Oncology Unit, IWK-Grace Health Centre, Halifax, NS, Canada, October 20, 2003

Yeung, PKF; “Biomarkers for vascular health and dementia”. Presented at the College of Pharmacy, Dalhousie University, Halifax, NS, Canada, June 19, 2003.

Yeung,PKF; “Pharmacokinetics and genetic approach to drug therapy: Role of RAS genotypes and neurohormone concentrations”. Presented at the Division of Cardiology, QEII Health Sciences Center, Halifax, NS, Canada, February 21st, 2003

Yeung, PKF; “Pharmacokinetics, drug metabolism and pharmacodynamics: What are their potential applications in drug product development ?” Presented to Sepracor Canada Ltd., Windsor, Nova Scotia, April 18th, 2002.

Yeung, PKF; “Diltiazem research: Where do we go from here ?” Presented to Biovail Technologies Ltd., Chantilly, VA, USA, March 7, 2002.

Yeung, PKF; “Pharmacokinetic and pharmacogenomic approach to drug therapy” Presented to Atlantic Canada Rx&D Companies, Halifax, Nova Scotia, Canada, December 4th, 2001.

Yeung, PKF; “Animal models for pharmacokinetics, metabolism and pharmacodynamic research”. A workshop presented to Health Canada, Ottawa, Ontario, Canada, October 26, 2001.

Yeung, PKF: “Pharmacokinetics and Genetic Approach to drug therapy” Presented to ACOA , Dalhousie University, Halifax, Nova Scotia, Canada, May 30, 2001.

Yeung, PKF: “Pharmacokinetics and rational (genetic) approach to drug therapy”. Presented at the Therapeutic Products Programme, Health Canada, Ottawa, Ontario, Canada, Sept 21, 2000.

Yeung,PKF: “Research program in Pharmacokinetics and Metabolism Laboratory, College of Pharmacy, Dalhousie University”. Presented at the Eli Lilly Canada Inc., Toronto, Ont., Canada, October 27th, 1999.

Yeung,PKF,: “Pharmacokinetics and pharmacodynamics of calcium antagonists: What is the point ?”. Presented at the AstraZeneca R&D Facility, Montreal, QC, Canada October 20th, 1999.

Yeung,PKF,: Pharmacokinetics and pharmacodynamics of diltiazem: Importance and future directions. Presented at the Biotechnology Centre, Acadia University, Wolfville, N.S., Canada, August 12, 1993.

Yeung PKF, Mosher,SJ, Li,R, Farmer,PS and Klassen GA. Effect of diltiazem metabolites on adenosine transport in whole blood. Presented at the 1st International Symposium on Pharmaceutical Research and Development, American Chinese Pharmaceutical Association, Kansas City, MO, U.S.A., May 28-31, 1993.

Yeung,PKF and Klassen GA,: Pharmacokinetics and pharmacodynamics of diltiazem: Where are we going ?. Presented at the School of Pharmacy, University of California, San Fransico (UCSF), April 15, 1993.

Yeung,PKF,: Pharmacokinetics and pharmacodynamics of calcium antagonists. Presented at a research meeting to the Division of Cardiology, Victoria General Hospital, Halifax, Nova Scotia, January 1991.

Quilliam,MA, Pleasance,S, Xie,M, Yeung,PKF,: Analysis of drugs and their metabolites by combined liquid chromatography-mass spectrometry and tandem mass spectrometry. Presented at the 73rd Canadian Chemical Conference and Exhibition, Halifax, NS, Canada, July 1990.

Yeung,PKF, Hubbard,JW, Tsui,B, and Midha,KK,: High performance liquid chromatographic analysis of diltiazem, chlorpromazine, and their metabolites. Presented at the Annual General Meeting and Conference of the Chemical Institute of Canada.(Atlantic Section), Monction, N.B., Canada, August 1988.