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Structure-activity analysis of quorum-sensing signaling peptides from Streptococcus mutans
Streptococcus mutans secretes and utilizes a 21-amino-acid signaling peptide pheromone to initiate quorum sensing for genetic competence, biofilm formation, stress responses, and bacteriocin production. In this study, we ...
Quorum sensing and bacterial social interactions in biofilms
Many bacteria are known to regulate their cooperative activities and physiological processes through a mechanism called quorum sensing (QS), in which bacterial cells communicate with each other by releasing, sensing and ...
The BceABRS four-component system regulates the bacitracin-induced cell envelope stress response in Streptococcus mutans
Streptococcus mutans is known to be resistant to bacitracin, a cyclic polypeptide antibiotic produced by certain species of the genus Bacillus. This property is often exploited in the isolation of S. mutans strains from ...
A novel target-specific, salt-resistant antimicrobial peptide against the cariogenic pathogen Streptococcus mutans
In this study, we constructed and evaluated a target-specific, salt-resistant antimicrobial peptide (AMP) that selectively targeted Streptococcus mutans, a leading cariogenic pathogen. The rationale for creating such a ...