Browsing Faculty of Medicine by Title
Now showing items 109-128 of 307
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FACT, the Bur Kinase Pathway, and the Histone Co-Repressor HirC Have Overlapping Nucleosome-Related Roles in Yeast Transcription Elongation
(2011-10)No abstract available. -
FACT, the Bur kinase pathway, and the histone co-repressor HirC have overlapping nucleosome-related roles in yeast transcription elongation
(2011-2011/)Gene transcription is constrained by the nucleosomal nature of chromosomal DNA. This nucleosomal barrier is modulated by FACT, a conserved histone-binding heterodimer. FACT mediates transcription-linked nucleosome disassembly ... -
Faster access to new drugs: Fault lines between Health Canada’s regulatory intent and Industry innovation practices
(Begell House, 2013)Since 2003, Health Canada has been undergoing regulatory modernization to “ensure that Canadians have faster access to the safe drugs they need.” As national health agencies develop policies to modernize the regulation ... -
Frailty, fitness and late-life mortality in relation to chronological and biological age
(BMC Springer Nature, 2002-02-27)Background: People age at remarkably different rates, but how to estimate trajectories of senescence is controversial. Methods: In a secondary analysis of a representative cohort of Canadians aged 65 and over (n = 2914) ... -
Framework for a web-based breast imaging learning module built on the open-source CAISIS platform and integrated with the new Breast Imaging EMR and existing breast imaging information technology infrastructure at Capital District Health Authority
(2012-09-11)This report describes the work performed during an 18-week summer internship in the Department of Diagnostic Radiology at Capital District Health Authority (CDHA) by Master of Health Informatics (MHI) candidate Mete ... -
Freeze resistance in rainbow smelt (Osmerus mordax): seasonal pattern of glycerol and antifreeze protein levels and liver enzyme activity associated with glycerol production
(2004-05)Rainbow smelt (Osmerus mordax) inhabit inshore waters along the North American Atlantic coast. During the winter, these waters are frequently ice covered and can reach temperatures as low as -1.9 degrees C. To prevent ... -
The freeze-avoidance response of smelt Osmerus mordax: initiation and subsequent suppression of glycerol, trimethylamine oxide and urea accumulation
(2002-05)Smelt (Osmerus mordax) were maintained at either ambient water temperature or approximately 5 degrees C and various aspects of their freeze-avoidance response were examined from early winter until early spring. Plasma ... -
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Fully Automated Wait Time Report Generator for Nova Scotia Breast Screening Program
(2012-05-29)In Canada, breast cancer is the most common type of cancer to afflict women. Although late stages are difficult to treat, prognoses for earlier stages are quite promising. Early detection is of paramount value in the ... -
Furthering an Innovative Approach to Caring for the Frail Elderly
(2016-03-28)People over the age of 65 (seniors) are the fastest growing demographic in Canada representing approximately 15% of the total national population in 2013 and expecting to grow to 24% by 2036 (Statistics Canada). The cost ... -
The Gcs1 Arf-GAP mediates Snc1,2 v-SNARE retrieval to the Golgi in yeast
(2006-04)No abstract available. -
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Gene-content evolution in discobid mitochondria deduced from the phylogenetic position and complete mitochondrial genome of Tsukubamonas globosa
(2014-01)The unicellular eukaryotic assemblage Discoba (Excavata) comprises four lineages: the Heterolobosea, Euglenozoa, Jakobida and Tsukubamonadida. Discoba has been considered as a key assemblage for understanding the early ... -
Genetic Assessment of Stationary Phase for Cells of the Yeast Saccharomyces-Cerevisiae
(1990-07)No abstract available. -
Genetic Evidence for a Mitochondriate Ancestry in the 'Amitochondriate' Flagellate Trimastix pyriformis
(2008-01)No abstract available. -
Genomic Characterization of Neoparamoeba pemaquidensis (Amoebozoa) and Its Kinetoplastid Endosymbiont
(2011-08)No abstract available. -
The geographic synchrony of seasonal influenza: A waves across Canada and the United States.
(Public Library of Science, 2011) -
Global challenges of implementing human papillomavirus vaccines
(BMC Springer Nature, 2011)Human Papillomavirus vaccines are widely hailed as a sweeping pharmaceutical innovation for the universal benefit of all women. The implementation of the vaccines, however, is far from universal or equitable. Socio- ... -
Glycerol production in rainbow smelt (Osmerus mordax) may be triggered by low temperature alone and is associated with the activation of glycerol-3-phosphate dehydrogenase and glycerol-3-phosphatase
(2006-03)Rainbow smelt (Osmerus mordax) accumulate high levels of glycerol in winter that serves as an antifreeze. Fish were subjected to controlled decreases in water temperature and levels of plasma glycerol, liver metabolites ...