Browsing Faculty of Graduate Studies Online Theses by Subject "Bacteria"
Now showing items 1-3 of 3
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Image Segmentation and Modelling of Host-Pathogen Dynamics of Salmonella
(2016-08-31)The pathogenic bacterium Salmonella enterica has recently been shown to hyper-replicate (HR) within the cytoplasm of epithelial cells. To better understand the mechanisms of HR, time-lapse fluorescence microscopy images, ... -
INFERRING ORTHOLOGOUS RELATIONSHIPS AND GENE TRANSFER IN MICROBIAL GENOMES AND METAGENOMES
(2019-11-28)Interest in microbial life and the progress of DNA sequencing technology has led to thousands of sequenced bacterial genomes. In this thesis I develop approaches to identify Lateral Gene Transfer (LGT) in metagenomes, ... -
Mechanisms by which Shigella flexneri impairs dendritic cell function: silencing the link between innate and adaptive immunity
(2015)Shigella flexneri is a Gram-negative bacterial pathogen that causes severe gastroenteritis in humans. Upon infection, Shigella invades the host colonic epithelium using a type III secretion system (T3SS) that is encoded ...