This thesis offers an allegorical reading of contemporary American literature’s critical response to neoliberalism’s reshaping of cultural and social value. Focusing on four literary recipients of the MacArthur Foundation ...

Type 1 (CB1) and Type 2 (CB2) Cannabinoid receptors form heteromers with unique pharmacology compared to CB1 or CB2 alone. We wanted to determine if the Tango β- arrestin2 luc reporter assay could measure heteromer-dependant ...

Sodium-ion batteries could one day be an inexpensive alternative to lithium-ion batteries. Many challenges need to be overcome before commercialization of a sodium-ion battery can take place. One of these challenges is the ...

The largest and most destructive earthquakes nucleate on the seismogenic parts of megathrust faults along subduction zones. Understanding the controls of rupture propagation in along-trench and dip direction is a key factor ...

Airway smooth muscle (ASM) contraction is a major contributor to bronchoconstriction, the narrowing of the airways observed in asthmatic airways. In vitro, ASM cells demonstrate the capacity to switch between more ...

Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) is the dominant tool used for mapping human brain function because it is non-invasive, does not use ionizing radiation, and offers ...

Hypothyroidism affects almost 2-5% of the world population and requires lifelong thyroxine replacement therapy. Oral Administration of levothyroxine (T4) encounters enormous pathophysiological and pharmacological challenges ...

Towns in southern Ontario, Canada, have experienced many changes since the mid-20th century due to urban sprawl around them. Residential suburbs with cul-de-sacs and big box stores have prioritized cars and drivers, while ...

Alveolar macrophages (AMs) are specialized, tissue-resident macrophages at the frontline of pulmonary defense against inhaled pathogens, and surfactant homeostasis. To perform these roles, AMs undergo cellular programming ...