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Tumor necrosis factor-{alpha} amplifies adipose-derived chemerin production and bioactivation
(2013-03-20)
Due to its escalating prevalence, obesity is becoming a leading cause of morbidity and mortality worldwide. Obesity is a complex health problem accompanied by metabolic abnormalities and low-grade inflammation that increases ...
DEVELOPMENT OF A CHEMOKINE-LIKE RECEPTOR 1 BIOASSAY TO STUDY THE IMPACT OF OBESITY ON ACTIVE CHEMERIN PRODUCTION IN OBESE HUMANS
(2014-12-17)
Prochemerin is an adipose-secreted molecule that is cleaved by extracellular proteases of the inflammatory, coagulation, and fibrinolytic cascades to active chemerin. Plasma and serum total chemerin (prochemerin + active ...
CHEMERIN REGULATES ADIPOSITY AND ENERGY HOMEOSTASIS
(2011-11-08)
Obesity, characterized by an excess of adipose tissue, is an established risk factor
for cardiovascular disease and type II diabetes. Different mechanisms linking obesity with
these comorbidities have been postulated but ...