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LOSS OF PRP4K IMPAIRS AUTOPHAGIC FLUX IN DICTYOSTELIUM DISCOIDEUM AND HUMAN CANCER CELLS
(2023-06-29)
The pre-mRNA splicing factor 4 kinase (PRP4K) is a haploinsufficient tumour suppressor conserved from Dictyostelium discoideum (D. discoideum) to humans. Here, we describe the first viable knockout (KO) model in D. discoideum, ...