Browsing Faculty of Graduate Studies Online Theses by Subject "apoptosis"
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The bitter taste receptor Tas2R14 is expressed in ovarian cancer and mediates apoptotic signaling
(2017-07-07)Bitter taste receptors (Tas2Rs) are a subfamily of G-protein coupled receptors expressed not only in the oral cavity but also in several extra-oral tissues and disease states. For example, mammary epithelial cells express ... -
The roles of cellular Inhibitor of Apoptosis Protiens 1 and 2 in the polarization of M1 and M2 macrophages
(2018-09-28)This thesis examined the effects of genetic ablation of the anti-apoptotic protein cIAP2 and SMAC mimetic (LCL161)-induced cIAP1 and cIAP2 suppression on the polarization of pro-inflammatory (M1) and anti-inflammatory (M2) ...