Browsing Faculty of Graduate Studies Online Theses by Title
Now showing items 942-961 of 7892
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Characterization of the potato late blight pathogen (Phytophthora infestans) in Canada and its implications on disease management and fungicide resistance
(2024-07-10)Late blight, caused by Phytophthora infestans, poses a major threat to potato and tomato crops globally. In Canada, increased incidence and severity of late blight have coincided with shifts in the genetic makeup of P. ... -
Characterization of the roles of neuronal cholesterol biosynthesis and ORP4 in hippocampal neurons and glia
(2018-01-05)Cholesterol is an essential component of cell membranes and plays important roles in cell signalling. The brain contains a quarter of the body’s total cholesterol pool, all of which is synthesized in situ by neurons and ... -
Characterization of The Viable but Non-Culturable Legionella pneumophila in Water and the Role of 3-Hydroxybutyrate Dehydrogenase in Its Formation
(2013-10-03)Legionella pneumophila, the causative agent of Legionnaires’ disease (LD), is an intracellular pathogen of freshwater protozoa that can also persist in the environment as a free-living bacterium. L. pneumophila has many ... -
Characterization of the virulence-related roles of the Legionella pneumophila chaperonin, HtpB, in mammalian cells.
(Dalhousie University, 2007) -
The Characterization of TiC and Ti(C,N) Based Cermets with and without Mo2C
(2014-03-05)Titanium carbide (TiC) and titanium carbonitride (Ti(C,N)) are both common components in hard, wear resistant ceramic-metal composites, or cermets. In this study the intermetallic nickel aluminide (Ni3Al) has been used as ... -
CHARACTERIZING A ROLE FOR NOS1AP IN CELLULAR MECHANOTRANSDUCTION
(2021-08-27)In a screen for proteins that interact with the phosphotyrosine binding (PTB) domain of NOS1AP we identified the b-integrin family of proteins. Fibronectin stimulated mouse embryonic fibroblasts (MEFs) from NOS1AP-/- mice ... -
Characterizing Arsenic Speciation and Metallomic Profiles in Toenail Samples of Atlantic Canadians: A Matched Case-Control Study of Breast, Cervical, Prostate, Urinary, and Skin Cancers
(2020-08-31)Chronic exposure to arsenic and metals has been associated with cancer risk. The research objectives were to 1) characterize the profiles of arsenic speciation and metallomes in the toenails of several cancer groups and ... -
Characterizing Artifact Generated by Passive Medical Devices in Modern Low-Field MRI: A Comparative Evaluation with Routine Clinical Practice
(2023-12-12)Following implantation of a medical device, MRI follow-up imaging is often performed to evaluate device function, assess healing, and monitor treatment progression. Metallic components in devices create artifacts that ... -
Characterizing Degradation in Organic Redox Flow Batteries
(2022-12-16)Organic redox flow batteries (ORFB)s are a promising energy storage technology that may facilitate the grid-integration of renewable energy. ORFB development is challenged by poor calendar lifetime and cycling stability. ... -
Characterizing Dynamic MRI Using Objective Image Quality Metrics
(2017-08-08)Quantitative mapping in dynamic magnetic resonance imaging (MRI) aims to recover quantitative parameters describing properties of patient tissues. However, quantitative mapping in dynamic MRI is difficult due to limitations ... -
CHARACTERIZING HOST TARGETED ANTIVIRALS THAT IMPAIR INFLUENZA A VIRUS PROTEIN SYNTHESIS
(2021-10-22)The plasticity of influenza A virus (IAV) genomes enables rapid evolution of resistance to antivirals that directly target viral proteins. By contrast, host-targeted antivirals have the potential to disrupt key steps in ... -
Characterizing metformin response and sensitivity biomarkers in breast cancer
(2018-09-28)The anti-diabetic drug metformin has been shown to exhibit broad in vitro and in vivo anti-neoplastic activity in various cancer types, including breast cancer. Despite numerous clinical trials ongoing, no targeted biomarkers ... -
Characterizing Mouse V1 Optogenetic-Mediated Rebound Effects
(2023-08-28)Cortical circuits comprise excitatory pyramidal (Pyr) cells and inhibitory interneurons that work together to perform neural computations. Optogenetic studies in mouse primary visual cortex (V1) have focused on (i) sketching ... -
CHARACTERIZING PRESENT AND FUTURE NITRATE LOADING IN A GROUNDWATER-DOMINATED AGRICULTURAL WATERSHED OF A COASTAL LAGOON
(2024-04-05)Basin Head is a coastal lagoon in northeastern PEI, where Nitrate-nitrogen (NO3-N) is conveyed from the agricultural watershed to the eutrophic lagoon via intertidal groundwater springs and groundwater-dominated tributaries. ... -
Characterizing recreational boating patterns based on GPS trajectory points.
(Dalhousie University, 2007) -
Characterizing Renal Tubular Epithelial Injury during Donation after Cardiocircualtory Death (DCD) and Possible Amelioration with PKX-001
(2024-06-26)Deceased donor kidneys from Donation after Circulatory Death (DCD) contribute significantly to transplantation yet pose challenges due to ischemia-reperfusion injury (IRI). This study characterizes renal tubular epithelial ... -
Characterizing Sources of Fecal Pollution at Four Urban Public Beaches in the Halifax Regional Municipality
(2016-03-30)Within the last few years several beaches in the Halifax Regional Municipality have closed frequently due to increased levels of E. coli within the beach waters. Enumeration, microbial enrichment, and genetic microbial ... -
Characterizing The Distinguishability Of Microbial Genomes
(2010-04-29)The field of metagenomics has shown great promise in the ability to recover microbial DNA from communities whose members resist traditional cultivation techniques, although in most instances the recovered material comprises ... -
CHARACTERIZING THE EFFECT OF COLONY STIMULATING FACTORS ON MACROPHAGE METABOLISM AND PHENOTYPE
(2023-08-24)Macrophages are a highly specialized group of immune cells and often referred to as sentinels of the immune system due to their ability to phagocytose cellular debris and pathogens, detect danger signals, and produce ... -
Characterizing the Effects of Experimental Glaucoma and Age on Retinal Ganglion Cell Function
(2023-08-30)Glaucoma is an optic neuropathy characterized by the progressive loss of retinal ganglion cells (RGCs). Clinical monitoring of disease progression uses gross structural changes as surrogate measures of RGC loss. Previous ...