Browsing Faculty of Graduate Studies Online Theses by Title
Now showing items 891-910 of 7504
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Characterization of the Diet-Microbiota-Gut-Brain Axis and its Role in Neuroinflammation
(2022-09-01)Neurodegenerative Diseases (NDs) are the leading causes of disability/death globally. The Diet-Microbiota-Gut-Brain (DMGB) axis is a promising area of research for NDs, investigating how intercommunication between diet, ... -
Characterization of the Early Cellular Mechanisms Promoting Myocardial Fibrosis
(2012-08-17)Myocardial fibrosis is a common pathological finding in patients with cardiovascular disease and is believed to be a major contributing factor in the development of end stage organ failure. Early events that promote the ... -
Characterization of the effects of RACK1 expression on mitochondrial physiology
(2023-07-31)Receptor for activated C kinase 1 (RACK1) is a multifunctional scaffolding protein that coordinates a variety of fundamental cellular processes in eukaryotic cells, and its aberrant expression has been implicated in the ... -
Characterization of the gene encoding a 40 kDa major antigen of the sealworm (Pseudoterranova decipiens).
(Dalhousie University, 1994) -
Characterization of the Interaction of Alpha4 Phosphoprotein with Novel Binding Partners: EDD E3 Ubiquitin Ligase and Poly(A)-Binding Protein
(2011-04-08)?4 phosphoprotein (also known as IGBP1) is a component of the mammalian target-of-rapamycin (mTOR) pathway that controls the initiation of translation and cell-cycle progression in response to nutrients and growth factors. ... -
Characterization of the Low- and High-Velocity Impact Performances of Fiber Reinforced Composites with Epoxy and Elium© Based Matrices
(2023-12-12)In recent years, there has been a gradual surge in the demand for fiber-reinforced plastics (FRPs). The implementation of FRPs can be observed across nearly every industry, ranging from advanced applications in aviation ... -
Characterization of the mechanical and hormonal sensitivity of glutamate receptor subtype expression on murine osteoclasts.
(Dalhousie University, 2005) -
Characterization of the mitochondrial genome and ribosomal RNAs of the colorless green alga Polytomella parva.
(Dalhousie University, 2002) -
CHARACTERIZATION OF THE PHOSPHODIESTERASE SUBTYPES THAT REGULATE MOUSE ATRIAL MYOCYTE ELECTROPHYSIOLOGY
(2012-11-20)Phosphodiesterases (PDEs) are the enzymes responsible for the hydrolysis of cyclic nucleotides including cAMP and cGMP. We recently discovered that natriuretic peptides elicit effects in the atrial myocardium via a PDE ... -
Characterization of the roles of neuronal cholesterol biosynthesis and ORP4 in hippocampal neurons and glia
(2018-01-05)Cholesterol is an essential component of cell membranes and plays important roles in cell signalling. The brain contains a quarter of the body’s total cholesterol pool, all of which is synthesized in situ by neurons and ... -
Characterization of The Viable but Non-Culturable Legionella pneumophila in Water and the Role of 3-Hydroxybutyrate Dehydrogenase in Its Formation
(2013-10-03)Legionella pneumophila, the causative agent of Legionnaires’ disease (LD), is an intracellular pathogen of freshwater protozoa that can also persist in the environment as a free-living bacterium. L. pneumophila has many ... -
Characterization of the virulence-related roles of the Legionella pneumophila chaperonin, HtpB, in mammalian cells.
(Dalhousie University, 2007) -
The Characterization of TiC and Ti(C,N) Based Cermets with and without Mo2C
(2014-03-05)Titanium carbide (TiC) and titanium carbonitride (Ti(C,N)) are both common components in hard, wear resistant ceramic-metal composites, or cermets. In this study the intermetallic nickel aluminide (Ni3Al) has been used as ... -
CHARACTERIZING A ROLE FOR NOS1AP IN CELLULAR MECHANOTRANSDUCTION
(2021-08-27)In a screen for proteins that interact with the phosphotyrosine binding (PTB) domain of NOS1AP we identified the b-integrin family of proteins. Fibronectin stimulated mouse embryonic fibroblasts (MEFs) from NOS1AP-/- mice ... -
Characterizing Arsenic Speciation and Metallomic Profiles in Toenail Samples of Atlantic Canadians: A Matched Case-Control Study of Breast, Cervical, Prostate, Urinary, and Skin Cancers
(2020-08-31)Chronic exposure to arsenic and metals has been associated with cancer risk. The research objectives were to 1) characterize the profiles of arsenic speciation and metallomes in the toenails of several cancer groups and ... -
Characterizing Artifact Generated by Passive Medical Devices in Modern Low-Field MRI: A Comparative Evaluation with Routine Clinical Practice
(2023-12-12)Following implantation of a medical device, MRI follow-up imaging is often performed to evaluate device function, assess healing, and monitor treatment progression. Metallic components in devices create artifacts that ... -
Characterizing Degradation in Organic Redox Flow Batteries
(2022-12-16)Organic redox flow batteries (ORFB)s are a promising energy storage technology that may facilitate the grid-integration of renewable energy. ORFB development is challenged by poor calendar lifetime and cycling stability. ... -
Characterizing Dynamic MRI Using Objective Image Quality Metrics
(2017-08-08)Quantitative mapping in dynamic magnetic resonance imaging (MRI) aims to recover quantitative parameters describing properties of patient tissues. However, quantitative mapping in dynamic MRI is difficult due to limitations ... -
CHARACTERIZING HOST TARGETED ANTIVIRALS THAT IMPAIR INFLUENZA A VIRUS PROTEIN SYNTHESIS
(2021-10-22)The plasticity of influenza A virus (IAV) genomes enables rapid evolution of resistance to antivirals that directly target viral proteins. By contrast, host-targeted antivirals have the potential to disrupt key steps in ... -
Characterizing metformin response and sensitivity biomarkers in breast cancer
(2018-09-28)The anti-diabetic drug metformin has been shown to exhibit broad in vitro and in vivo anti-neoplastic activity in various cancer types, including breast cancer. Despite numerous clinical trials ongoing, no targeted biomarkers ...