Browsing by Subject "Glutamate"
Now showing items 1-3 of 3
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The Association of Anterior Cingulate Cortex Glutamate and Clozapine Eligibility In an Early Psychosis Sample
(2023-07-27)Background: The ability to identify patients who may benefit from clozapine at the earliest opportunity is important for maximizing long term outcomes in schizophrenia. Patients that meet criteria for treatment resistance ... -
Behavioural and neuronal activation after microinjections of AMPA and NMDA into the perifornical lateral hypothalamus in rats
(Elsevier, 2011-10-31)The perifornical lateral hypothalamic area (PeFLH), which houses orexin/hypocretin (OX) neurons, is thought to play an important role in arousal, feeding, and locomotor activity. The present study examined behavioural ... -
EXPLORING THE ROLE OF MITOCHONDRIAL CHOLESTEROL IN NIEMANN-PICK TYPE C DISEASE
(2016-01-19)Niemann-Pick type C (NPC) disease is an autosomal recessive neurodegenerative disorder caused by mutations in Npc1 or Npc2 gene. Npc1 and Npc2 encode a late-endosomal transmembrane and lumenal cholesterol-binding domain ...