Browsing by Subject "Molecular Biology"
Now showing items 1-5 of 5
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GENETIC VARIANTS OF ERYTHROPOIETIN AND THEIR BIOLOGICAL SIGNIFICANCE
(2023-08-16)Erythropoietin (EPO) is a hematopoietic cytokine with a multitude of functions, that are erythropoietic, metabolic or cytoprotective. The erythropoietic functions of EPO have led to the development of many erythropoietic ... -
INVESTIGATING THE ROLE OF MLLT11 IN CORTICAL DEVELOPMENT
(2023-08-18)The formation of connections within the mammalian neocortex is highly regulated by both extracellular guidance mechanisms and intrinsic gene expression programs. Dysregulation of these programs has been shown to cause a ... -
Loss of mitochondrial quality control protein Yme1 is deleterious to the viability of yeast lacking tafazzin.
(2016-01-19)The Saccharomyces cerevisiae TAZ1 gene is an orthologue of human TAZ; both encode the protein tafazzin. Tafazzin is a transacylase that transfers acyl chains with unsaturated fatty acids from other phospholipids to ... -
The Role of NCK in DCC-Sensitive Spinal Cord Circuits
(2016-01-19)Non-Catalytic region of tyrosine Kinase (NCK) adaptor proteins connect cell surface receptors to the actin cytoskeleton. In the central nervous system loss of NCK proteins leads to a hopping like phenotype¬. We were ... -
Site-Specific Tyrosine Phosphorylation of the Type III Secretion Chaperone CesT Regulates Effector Hierarchy and Promotes Enteropathogenic Escherichia coli Intestinal Disease
(2017-08-22)Enteropathogenic E. coli (EPEC) is a global enteric pathogen that causes serious gastrointestinal disease and inflicts a significant burden on healthcare systems worldwide. Recent phosphoproteomic studies suggest that ...