Browsing by Subject "Epigenetics"
Now showing items 1-6 of 6
-
Effects of Prenatal Stress and/or Forebrain Atrx Deficiency in C57/B6 Male Mice on Maternal Care and Emotional, Cognitive and Social Development
(2018-12-18)Early life experience influences the developing brain, notably in areas related to stress regulation, cognition and social behaviours. During perinatal development, the brain exhibits high plasticity, and environmental ... -
Effects of Prenatal Stress and/or Forebrain ATRX Deficiency in C57BL/6 Mice on Cellular Metabolism, DNA Damage, ATM Promoter Methylation and Gene Expression
(2021-08-26)Early life experiences and maternal care influence brain development, in areas that support stress regulation, cognition, and social behaviour. Studies suggest that sustained changes in gene expression in response to ... -
GENOMIC IMPRINTING IN Drosophila melanogaster: EPIGENETIC REGULATION OF THE Dp(1;f)LJ9 IMPRINTED DOMAIN
(2010-08-30)Genomic imprinting is an epigenetic phenomenon whereby the expression of a gene, chromosomal region, or entire chromosome, depends on the sex of the transmitting parent. Imprinting results in an otherwise fully functional ... -
INTER-KINGDOM EPIGENETICS: CHARACTERIZATION OF MAIZE B1 TANDEM REPEAT-MEDIATED SILENCING IN DROSOPHILA MELANOGASTER
(2010-09-02)Transgenic organisms are a valuable tool for studying epigenetics, as they provide significant insight into the evolutionary conservation of epigenetic control sequences, the interacting proteins, and the underlying molecular ... -
Navigating memory and neuron identity with the COMPASS complexes
(2023-08-24)Epigenetic post-translation modifications are thought to be involved in the maintenance of postmitotic neuron subtypes, however, their role in maintaining differentiated cell-type specific identities is not clear. Previous ... -
Zebrafish Tools To Combat Acute Myeloid Leukaemia – The Nucleoporin 98 kiloDalton—Homeobox A9 (NUP98-HOXA9) Fusion Oncogene Drives Myeloproliferation By Upregulating DNA (Cytosine-5-)-Methyltransferase 1 (dnmt1)
(2018-02-12)We need to better understand the genetic mechanisms that transform normal blood cells into acute myeloid leukaemia (AML). Overall survival is improving for children and adults with AML, but traditional therapies can be ...