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Recent Submissions

  • Item type: Item , Access status: Embargo ,
    Utilizing Metabolomics and Genomics to Enhance Parasite Resistance in Sheep
    (2025-11-06) Jawad, Hamza; Not Applicable; Master of Science; Faculty of Agriculture; Received; Dr. Luiz F. Brito; No; Dr. Younes Miar; Dr. John Gilleard; Dr. Ghader Manafiazar
    Gastrointestinal parasites, particularly Haemonchus contortus, significantly compromise sheep farm profitability. We integrated metabolomics and genomics data from 78 Rideau Arcott ewe lambs during controlled infection to develop diagnostic and genetic tools for parasite management. Metabolomic analysis identified candidate biomarkers—including indole acetic acid and trans-hydroxyproline—that demonstrated the potential to detect subclinical infections with progressive diagnostic accuracy. After validation, these metabolites could enable earlier diagnosis and treatment in precision livestock systems. Whole-genome sequencing revealed copy number variation patterns associated with parasite resistance and susceptibility. We identified key genes influencing immune function and disease resistance, particularly CLCA1 duplication. These findings provide practical tools for integrated parasite management: metabolite candidate biomarkers can be incorporated into field-deployable point-of-care diagnostics for on-farm detection, while genomic markers enable genomic selection for parasite resistance in breeding programs. Implementation of these diagnostic and genetic tools will help the Canadian sheep industry reduce anthelmintic dependence while improving productivity.
  • Item type: Item , Access status: Embargo ,
    Investigation of Gas Evolution and Safety of Materials for Lithium and Sodium-Ion Batteries
    (2025-10-30) Tulloch, Meredith; Not Applicable; Master of Applied Science; Department of Process Engineering and Applied Science; Not Applicable; n/a; Not Applicable; Jeff Dahn; Alison Scott; Michael Metzger
    The increased use of rechargeable batteries is one strategy in the fight against climate change, as a higher battery usage allows for the integration of more renewable energy sources. However, the development of batteries, particularly sodium-ion batteries, is still underway, with improvements to energy density and lifetime as the main research goals. Changes to the cell chemistry, the use of electrolyte additives, alloying negative electrode materials, and increasing the upper cut-off voltage to achieve higher cell capacity are all viable options to improve cell performance. This work explores electrolyte additives and Pb as a negative electrode material in sodium ion cells through on-line electrochemical mass spectrometry to investigate how these components impact the gases that are produced during battery operation. The electrolyte additives sodium difluorophosphate and 1,3,2-dioxathiolane 2,2-dioxide were studied in comparison to a control electrolyte through half cell tests and storage tests with notable differences in the gases evolved. Pb was compared to hard carbon and a blended electrode containing both materials to study the differences in carbonate and ether based electrolytes. Lastly, accelerating rate calorimetry was used to characterize the safety limits of a layered oxide positive electrode material for lithium-ion cells. Various upper cut-off voltages were used to probe the safety limitations of the material. Further investigation into the thermal response of the layered oxide positive electrode was completed using x-ray diffraction analysis. Overall, this work provides results for the gases produced from various cell chemistries in sodium-ion batteries, as well as the thermal responses seen in lithium-ion positive electrodes.
  • Item type: Item , Access status: Open Access ,
    Integrating Hydrologic Climate Projections into Source Water Protection Planning in Small Atlantic Canadian Communities
    (2025-10-30) Dort, Amber; Not Applicable; Master of Applied Science; Department of Civil and Resource Engineering; Not Applicable; n/a; Not Applicable; Graham Gagnon; Andrew Medeiros; Lauren Somers
    Climate change is a critical driver of hydrologic change in Atlantic Canada, where small utilities often manage source water with limited capacity. This research supports small communities in assessing climate change impacts on water supplies and identifies efficient modelling approaches. Lake George, the water source for Yarmouth, Nova Scotia, served as the study site. The hydrological system was characterized using public data and field observations, followed by three modelling schemes of varying complexity to simulate lake water balance. Downscaled climate projections were applied to evaluate future impacts. Lake levels were most sensitive to summer precipitation, followed by temperature and usage. Complex models with site-specific hourly data outperformed the simpler daily model, projecting more extreme impacts, including levels dropping below an outlet but not the treatment intake. While complex models provide quantitative insight, simpler models can guide qualitative assessments. Findings informed Yarmouth's Source Water Protection Plan and can guide similar communities.
  • Item type: Item , Access status: Open Access ,
    Decent Work and Temporary Stay: An Overview of the ILO Agri-Food Guidelines Affecting Migrant Workers in Canada
    (McMaster University, 2025-11-07) Bejan, Raluca; Allain, Kristi A; Lyubchenko, Olena
    This report uses a realist review methodology, focusing on three Canadian provinces – Alberta, New Brunswick, and Ontario – to examine labour protections in the meat packing, agriculture, and seafood processing industries. The research team examined grey and academic literature on working conditions and social protections for temporary foreign workers, a group of workers particularly vulnerable to labour exploitation. The report synthesizes scholarly and grey literature from January 2020 to December 2024, using a comprehensive keyword strategy to address the realist review questions of What works? For whom? Under what circumstances? And how? – questions that pertain to the design and implementation of protective occupational guidelines across the three provinces.
  • Item type: Item , Access status: Open Access ,
    Africville: Reparation in the Paradoxical Legal Construction and Deconstruction of an African Canadian Community
    (2001-06) Sparks, Corrine E.; Not Applicable; Master of Laws; Faculty of Law; Not Applicable; unknown; Not Applicable; Philip V. Girard; Leon E. Trakman; Jennifer K. Bankier
    This thesis examines the circumstances surrounding the relocation of the community of Africville with a view to reparations for the former Africville residents. There is a discussion of the theory of reparations. From a Critical Race perspective this thesis explores the historical significance of Africville in relation to other Black Nova Scotia communities. It also explores the involvement of Blacks in relation to the early colonial settlement of Nova Scotia. From personal interviews there is a documentation of the human toll which was paid by the former Africville residents when they were relocated in 1969. These anecdotal accounts also illustrate the inequities involved with the mass relocation of an entire community. There is also a brief comparison of redress for Japanese Canadians with a view to how Japanese Canadians were successful in obtaining redress for their years of suffering as a result of mass relocation and confiscation of their property in British Columbia in the 1940's during the Second World War. In order to further contextualize the historical experience of Nova Scotian Blacks, there is an examination of how the Black community has progressed since the Africville relocation. The social advocacy which was lacking during the Africville relocation has now developed with numerous professional associations which may be able to assist Africville residents as they seek redress. There is a review of two legal claims; unjust enrichment and unconscionability. Both of these equitable claims may prove helpful during litigation for the Africville residents. These two claims are based in equity and lend themselves to judicial discretion as well as principles developed through caselaw. Equitable remedies are also examined. These legal alternatives are discussed in light of two main jurisprudential theories; Legal Realism and Critical Race Theory. This discussion reveals the importance of jurisprudential approaches in the resolution of race based litigation. Finally, there are recommendations for how the Africville aftermath can be resolved so that the Black community can begin to heal in the face of horrendous racial injustice. If these measures are implemented, race relations could be greatly improved in the province of Nova Scotia.
  • Item type: Item , Access status: Open Access ,
    Can Video Games Improve Adherence to Treatment in Children with Chronic Diseases?
    (2009-10) Kharrazi, Hadi Hadj Karim; Not Applicable; Doctor of Philosophy; Faculty of Computer Science; Received; A. Mokashi; Not Applicable; C. Watters; P. McGrath; A. Otley; M. Shepherd
    This research explored the use of interactive information technology applications for children with long term treatment regimens in which adherence is a key factor in the success of the treatment. Behavior change models play a major role in enhancing adherence to treatment in patients with chronic conditions. In this research, a conceptual framework was designed based on the Theory of Planned Behavior. The conceptual framework was mapped to game enjoyment elements to develop a game framework. The framework learned from the patient's situation based on the patient's adherence rate and measured behavioral determinants; and then the game adapted itself to the new situation and created new strategies to empower the patient in order to reinforce positive intention and behavior on the part of the patient. The game framework was tested with children in two separate user studies including IBD (Inflammatory Bowel Disease) and Type I diabetes patients. Both user studies implemented a mixed between-group and within-subject methodology. Two versions of the game were developed, one with the embedded conceptual framework and another without. Participants were assigned randomly to the treatment and control groups. The treatment group played the game with the conceptual framework and the control group played the game without the theoretical framework. In the middle of the study, each group switched to the other game type and experienced a within-subject change. The results were analyzed by GLM-ANOV A and Mix-Modeling. GLM-ANOV A showed a significant effect of game type (conceptual framework) on both behavioral intention and adherence to treatment regimens in patients with Inflammatory Bowel Disease and patients with Type I diabetes. Mix-modeling showed a significant effect of game type, time and the interaction between them on both behavioral intention and adherence to treatment regimens in both user studies.