Browsing Dentistry Faculty Research, Publications and Presentations by Submit Date
Now showing items 21-29 of 29
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The BceABRS four-component system regulates the bacitracin-induced cell envelope stress response in Streptococcus mutans
Streptococcus mutans is known to be resistant to bacitracin, a cyclic polypeptide antibiotic produced by certain species of the genus Bacillus. This property is often exploited in the isolation of S. mutans strains from ... -
A novel target-specific, salt-resistant antimicrobial peptide against the cariogenic pathogen Streptococcus mutans
In this study, we constructed and evaluated a target-specific, salt-resistant antimicrobial peptide (AMP) that selectively targeted Streptococcus mutans, a leading cariogenic pathogen. The rationale for creating such a ... -
Quorum sensing and bacterial social interactions in biofilms
Many bacteria are known to regulate their cooperative activities and physiological processes through a mechanism called quorum sensing (QS), in which bacterial cells communicate with each other by releasing, sensing and ... -
Structure-activity analysis of quorum-sensing signaling peptides from Streptococcus mutans
Streptococcus mutans secretes and utilizes a 21-amino-acid signaling peptide pheromone to initiate quorum sensing for genetic competence, biofilm formation, stress responses, and bacteriocin production. In this study, we ... -
Detachment of Streptococcus mutans biofilm cells by an endogenous enzymatic activity
Previous studies have shown that Streptococcus mutans NG8 possesses an endogenous surface protein-releasing enzyme (SPRE) activity that liberates its own surface proteins (S. P. Lee, Infect. Immun. 60:4032-4039, 1992). The ... -
A year of research and collaboration supporting the phased reopening of primary oral health care service delivery in Nova Scotia during the COVID-19 pandemic: March 2020 to March 2021
Executive Summary: The timing of this report marks just over one year since the province of Nova Scotia, in response to the COVID-19 global pandemic, announced the closure of all but emergency oral health services in March ... -
Exploring Fifty Years of Scholarship Across the Curriculum (SAC) and Table Clinics at the Dalhousie Faculty of Dentistry
For some, doing research can be ominous and uncertain. From time to time, one may hear in the halls of the dental building, in tones of frustration, “Why do we need to do research to become a good clinician!?” I had the ... -
Policy Changes and Anxiety in Canadian Dental Hygienists During the COVID-19 Pandemic (Postprint)
Background: The COVID-19 outbreak has profoundly affected the dental hygiene workforce in Canada, revealing gaps in psychological factors affecting oral healthcare providers in response to policy changes. The objective of ...